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估算加拉帕戈斯群岛牛布鲁氏菌病无疫的概率。

Estimating the probability of freedom from bovine brucellosis in the Galapagos Islands.

作者信息

Gioia G, Vinueza R L, Cruz M, Jay M, Corde Y, Marsot M, Zanella G

机构信息

Laboratory for Animal Health, Epidemiology Unit, ANSES, University Paris Est, Maisons-Alfort, France.

UBL, MAN-IMAL IDEFI ANR 11-0003, Atlantic National College of Veterinary Medicine, Food Science and Engineering (Oniris), Nantes, France.

出版信息

Epidemiol Infect. 2018 Sep 19;147:e9. doi: 10.1017/S0950268818002534.

Abstract

Bovine brucellosis is a worldwide zoonotic disease that still burdens several countries in the Mediterranean, Asia, Africa and Latin America. Although the disease is present in Ecuador, the Galapagos Islands seem to be free from the disease based on a survey conducted in 1997 where all tested animals showed negative results. This study aimed at estimating the probability of freedom from brucellosis in this Ecuadorian province in 2014. A survey was implemented on the three main cattle-producing islands of the province: Santa Cruz, Isabela and San Cristóbal. Thirty-three cattle farms and 410 cattle were tested for brucellosis using the Rose Bengal test and indirect ELISA. All animals showed negative results for both tests. Probability of freedom was estimated at 98%, 91% and 88% for Santa Cruz, Isabela and San Cristóbal, respectively, considering a herd-level design seroprevalence of 20% and animal-level design seroprevalence of 15%, and assuming a perfect specificity of the survey. The negative results found in 1997 and present surveys suggest that the Galapagos Islands are free from bovine brucellosis.

摘要

牛布鲁氏菌病是一种全球性人畜共患病,仍给地中海地区、亚洲、非洲和拉丁美洲的多个国家带来负担。尽管厄瓜多尔存在这种疾病,但根据1997年进行的一项调查,加拉帕戈斯群岛似乎没有这种疾病,当时所有接受检测的动物结果均为阴性。本研究旨在估计2014年该厄瓜多尔省份无布鲁氏菌病的概率。在该省三个主要养牛岛屿:圣克鲁斯岛、伊莎贝拉岛和圣克里斯托瓦尔岛开展了一项调查。使用玫瑰红试验和间接酶联免疫吸附测定法对33个养牛场的410头牛进行了布鲁氏菌病检测。所有动物的两项检测结果均为阴性。考虑到畜群水平设计血清阳性率为20%,动物水平设计血清阳性率为15%,并假设调查具有完美的特异性,圣克鲁斯岛、伊莎贝拉岛和圣克里斯托瓦尔岛无病概率分别估计为98%、91%和88%。1997年及本次调查得到的阴性结果表明,加拉帕戈斯群岛没有牛布鲁氏菌病。

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