Bonilla-Aldana D Katterine, Trejos-Mendoza Adrián Esteban, Pérez-Vargas Soffia, Rivera-Casas Estefany, Muñoz-Lara Fausto, Zambrano Lysien I, Arteaga-Livias Kovy, Ulloque-Badaracco Juan R, Alarcon-Braga Esteban A, Hernandez-Bustamante Enrique A, Al-Kassab-Córdova Ali, Benites-Zapata Vicente A, Rodriguez-Morales Alfonso J
Research Unit, Universidad Continental, Huancayo, Peru.
Faculty of Veterinary Medicine, Fundación Universitaria Autónoma de las Américas-Institución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia.
New Microbes New Infect. 2023 Aug 24;54:101168. doi: 10.1016/j.nmni.2023.101168. eCollection 2023 Sep.
Bovine brucellosis is a significant public health problem in countries with economic and zoonotic implications. Although relevant, there are no previous systematic reviews about bovine brucellosis in Latin America.
We performed a systematic literature review in five data-bases to assess the seroprevalence of Brucella in cattle. A meta-analysis with a random-effects model was performed to calculate the pooled prevalence and 95% confidence intervals (95%CI). In addition, measures of heterogeneity (Cochran's Q statistic and I test) were reported.
The literature search yielded 3,403 articles, of which 65 studies were fully valid for analysis. The pooled seroprevalence for Brucella in bovine (n = 46,883,177) was 4.0% (95%CI: 3.0%-5.0%; p < 0.001), and Venezuela was the country with the highest prevalence (16.0%). By regions, the highest seroprevalence is in Central America and the Caribbean islands (8.0%,95%CI: 3.0%-15.0%; p < 0.001, I = 99.85).
Some countries reported still relevant seroprevalences of bovine brucellosis, especially at the Central America and Caribbean islands. Multiple factors may influence the survival and spread of pathogens in the environment; farms located in regions bordering forest areas, in areas of difficult access to the veterinary service; extensive beef herds raised at pastures with different age and productive groups inter-mingled, and minimal concerns regarding hygiene practices and disease prevention measures. Bovine brucellosis has not been eliminated and needs to be considered with new tools for prevention and control, especially being a zoonosis.
牛布鲁氏菌病在具有经济和人畜共患病影响的国家是一个重大的公共卫生问题。尽管相关，但此前尚无关于拉丁美洲牛布鲁氏菌病的系统综述。
我们在五个数据库中进行了系统的文献综述，以评估牛群中布鲁氏菌的血清阳性率。采用随机效应模型进行荟萃分析，以计算合并患病率和95%置信区间（95%CI）。此外，还报告了异质性测量指标（ Cochr an's Q统计量和I²检验）。
文献检索共获得3403篇文章，其中65项研究完全符合分析要求。牛群中布鲁氏菌的合并血清阳性率（n = 46,883,177）为4.0%（95%CI：3.0%-5.0%；p < 0.001），委内瑞拉的患病率最高（16.0%）。按地区划分，血清阳性率最高的是中美洲和加勒比群岛（8.0%，95%CI：3.0%-15.0%；p < 0.001，I² = 99.85）。
一些国家报告的牛布鲁氏菌病血清阳性率仍然较高，特别是在中美洲和加勒比群岛。多种因素可能影响病原体在环境中的存活和传播；位于与森林地区接壤的地区、兽医服务难以到达的地区的农场；在牧场饲养的大量肉牛群，不同年龄和生产群体混养，以及对卫生习惯和疾病预防措施的关注最少。牛布鲁氏菌病尚未消除，需要用新的预防和控制工具来加以考虑，特别是作为一种人畜共患病。
