使用 γ-环糊精实现了扩展烯烃的立体和区域选择性光环加成反应。
Stereo- and regioselective photocycloaddition of extended alkenes using γ-cyclodextrin.
机构信息
Department of Chemistry, University of Nebraska Kearney, NE-68845, USA.
出版信息
Org Biomol Chem. 2018 Oct 3;16(38):6870-6875. doi: 10.1039/c8ob01966e.
Abstract
Photoexcitation of dibenzalacetones (1a-d) in homogeneous media and solid state yields a mixture of products with poor conversions. Irradiation of the reactants complexed to γ-cyclodextrin predominantly affords a single dimer (syn adduct 6) despite the possibility for several monomeric and dimeric products. High selectivity in the cavitand-mediated reaction along with the structural characterization of the inclusion complex provides insight into the supramolecular interactions that drive the self-assembly of the host-guest system.
摘要
在均相介质和固态中，二苯甲缩醛（1a-d）的光激发产生转化率差的产物混合物。尽管可能存在几种单体和二聚体产物，但将反应物与γ-环糊精络合进行辐照主要得到单一的二聚体（顺式加合物 6）。在主体分子介导的反应中具有高选择性，以及包含复合物的结构特征，深入了解了驱动主体-客体体系自组装的超分子相互作用。
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