Vogel H M, Friedrich K, Koch H
Endoscopy. 1986 Sep;18(5):185-7. doi: 10.1055/s-2007-1018368.
We investigated the question as to whether benign cholangiofibromas of the liver (biliary microharmatomas) show specific structures in ultrasound. Patients with single, sporadic, multiple or diffuse cholangiofibromas (n = 53), detected by laparoscopy and verified by histology, were examined by ultrasound. The single and sporadic type (n = 30) could not be detected by US. In patients with the multiple and diffuse type (N = 23) the descriptive US finding was: "increased content of fibrous tissue, cirrhotic transformation possible". Thus we conclude that patients with non-specific alterations of the liver in the ultrasound image must undergo further investigation by laparoscopy. Blind biopsy is not capable of verifying the presence of cholangiofibromas.