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[β-肾上腺素能受体阻断对猫骨骼肌血管床滤过-吸收功能的影响]

[Effect of beta-adrenoreceptor blockade on the filtration-absorption function of the vascular bed of the skeletal musculature of the cat].

作者信息

Savel'ev A K

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1986 Sep;72(9):1269-74.

PMID:3023149
Abstract

Perfusion of the cat hindlimb with alternating stabilization of pressure and blood flow in response to electrical stimulation of sympathetic fibers prior to and after blockade of beta-adrenoreceptors decreased considerably changes of the capillary filtration coefficient and the capillary hydrostatic pressure, improving changes of the filtration-absorption balance induced with the stimulation. beta-Adrenoreceptors of vascular bed are shown to take part in neurogenic regulation of both the exchange and the capacitance functions of the vascular bed, as well as its resistance function. Activation of sympathetic fibers seems to enhance permeability of the vascular wall.

摘要

在阻断β-肾上腺素能受体之前和之后,对交感神经纤维进行电刺激,猫后肢灌注时压力和血流交替稳定,这大大降低了毛细血管滤过系数和毛细血管静水压的变化,改善了刺激引起的滤过-吸收平衡变化。结果表明,血管床的β-肾上腺素能受体参与了血管床交换功能、容量功能及其阻力功能的神经源性调节。交感神经纤维的激活似乎会增强血管壁的通透性。

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