Junior Resident, Department of Preventive and Social Medicine, All India Institute of Hygiene and Public Health, Kolkata, West Bengal, India.
Director-Professor, Department of Preventive and Social Medicine, All India Institute of Hygiene and Public Health, Kolkata, West Bengal, India.
Indian J Public Health. 2018 Jul-Sep;62(3):175-181. doi: 10.4103/ijph.IJPH_258_18.
Vitamin D deficiency/Vitamin D Insufficiency (VDI) is now recognized as a pandemic. Cutaneous exposure to ultraviolet-B causes photolysis of epidermal 7-dehydrocholesterol, converting it to pre-Vitamin D3 (precholecalciferol), which then undergoes isomerization to form the stable hormone Vitamin D3.
The objectives of the study is to determine the status of Vitamin D level among the adults residing in a rural area of West Bengal and to find out the optimal cutoff of the sun exposure for Vitamin D sufficiency.
This study was a rural community based cross-sectional study. It was done from May 2016 to April 2017 among 197 adults residing in a rural block of West Bengal. Data were collected by interviewing the respondents with the help of a structured pre-tested pre-designed schedule. After interviewing, every individual was examined for height and weight and blood was collected for serum Vitamin 25-(OH) D. Receiver Operating Characteristic (ROC) curves were utilized to find out optimum cut-off for sun exposure using Youden's index. Binary logistic regression was performed to find out the associates of high sun exposure. All analysis was done using R.
Overall VDI was found in 133 (67.5%). Among them, 102 (51.8%) were female. On ROC curve for veritable sun exposure for Vitamin D sufficiency, area under curve was 0.7841 which signifies veritable sun exposure as a good screening tool.
Proper information, education, and communication material regarding various aspects of sun exposure and Vitamin D should be prepared with due consultation of field experts and disseminated to increase awareness among the community.
维生素 D 缺乏/不足(VDI)现在被认为是一种大流行病。皮肤暴露在紫外线下会导致表皮 7-脱氢胆固醇发生光解,转化为前维生素 D3(前胆钙化醇),然后进行异构化形成稳定的激素维生素 D3。
本研究旨在确定孟加拉国农村地区成年人的维生素 D 水平状况,并找出获得维生素 D 充足所需的最佳日照时间。
本研究是一项农村社区的横断面研究。于 2016 年 5 月至 2017 年 4 月在孟加拉国一个农村地区的 197 名成年人中进行。通过结构化预测试预设计的问卷采访调查来收集数据。访谈结束后,对每位受访者进行身高和体重检查,并采集血液检测血清维生素 25-(OH)D。利用约登指数(Youden's index),通过接收者操作特征(ROC)曲线来寻找最佳日照时间的截断值。采用二元逻辑回归分析寻找高日照时间的相关因素。所有分析均使用 R 进行。
总体 VDI 发生率为 133 例(67.5%)。其中,102 例(51.8%)为女性。在评估维生素 D 充足所需真实日照时间的 ROC 曲线中,曲线下面积为 0.7841,表明真实日照时间是一种较好的筛查工具。
应适当咨询现场专家,准备有关日照和维生素 D 各方面的适当信息、教育和宣传材料,并向社区传播,以提高社区的认识。