International Union Against Tuberculosis and Lung Disease (The Union), Paris, France, London School of Hygiene & Tropical Medicine, London, UK.
International Union Against Tuberculosis and Lung Disease (The Union), Paris, France, The Union, Beijing, China.
Int J Tuberc Lung Dis. 2018 Oct 1;22(10):1117-1126. doi: 10.5588/ijtld.17.0677.
Integrating the management and care of communicable diseases, such as tuberculosis (TB) and human immunodeficiency virus/acquired immune-deficiency syndrome (HIV/AIDS), and non-communicable diseases, particularly diabetes mellitus (DM), may help to achieve the ambitious health-related targets of the Sustainable Development Goals (SDG 3.3 and 3.4) by 2030. There are five important reasons to integrate. First, we need to integrate to prevent disease. In sub-Saharan Africa, in particular, HIV infection is the main driver of the TB epidemic, and antiretroviral therapy combined with isoniazid preventive therapy (IPT) can reduce TB case notification rates. In Asia, DM is another important driver of the TB epidemic, and preventing or controlling DM can reduce the risk of TB. Second, we need to integrate to diagnose cases. Between a third to a half of those living with HIV, TB or DM do not know they have the disease, and bi-directional screening, whereby TB patients are screened for HIV and DM or people living with HIV and DM are screened for TB, can help to identify these 'missing cases'. Third, we need to integrate to better treat and manage patients who have a combination of two or more of these diseases, so that treatment success and retention on treatment can be optimised. Fourth, we should integrate to ensure better infection control practices for both TB and HIV infection in health facilities and congregate settings, such as prisons. Finally, we should integrate and learn how to monitor, record and report, particularly in relation to the cascade of events implicit in the HIV/AIDS and TB 90-90-90 targets.
将传染病(如结核病[TB]和人类免疫缺陷病毒/获得性免疫缺陷综合征[HIV/AIDS])和非传染性疾病(特别是糖尿病[DM])的管理和护理相结合,可能有助于实现 2030 年可持续发展目标(SDG 3.3 和 3.4)中雄心勃勃的与健康相关的目标。有五个重要的原因需要整合。首先,我们需要整合来预防疾病。特别是在撒哈拉以南非洲,HIV 感染是结核病流行的主要驱动因素,而联合抗逆转录病毒疗法加异烟肼预防性治疗(IPT)可以降低结核病发病率。在亚洲,DM 是结核病流行的另一个重要驱动因素,预防或控制 DM 可以降低结核病的风险。其次,我们需要整合来诊断病例。三分之一到一半的 HIV、TB 或 DM 患者不知道自己患有这些疾病,而双向筛查,即对 TB 患者进行 HIV 和 DM 筛查,或对 HIV 和 DM 患者进行 TB 筛查,可以帮助识别这些“漏诊病例”。第三,我们需要整合来更好地治疗和管理同时患有两种或两种以上疾病的患者,以优化治疗成功率和治疗保留率。第四,我们应该整合,以确保在卫生机构和聚集场所(如监狱)更好地进行结核病和 HIV 感染的感染控制实践。最后,我们应该整合并学习如何监测、记录和报告,特别是在与 HIV/AIDS 和 TB 90-90-90 目标中隐含的事件级联有关的方面。