Department of Cellular and Molecular Medicine, Brain and Mind Research Institute, and Neuroscience Program, University of Ottawa, Ottawa, ON, Canada.
Department of Cellular and Molecular Medicine, Brain and Mind Research Institute, and Neuroscience Program, University of Ottawa, Ottawa, ON, Canada.
Neuron. 2018 Sep 19;99(6):1099-1101. doi: 10.1016/j.neuron.2018.09.011.
In this issue of Neuron, Schäffner et al. (2018) discover multiple effects of the Forkhead Box O (FoxO) transcription factor family on the different stages of adult neurogenesis, including the genesis of dendrites and spines regulated by FoxO-dependent autophagic activity.
在本期《神经元》中, Schäffner 等人(2018 年)发现叉头框 O(FoxO)转录因子家族对成年神经发生的不同阶段有多种影响,包括受 FoxO 依赖性自噬活性调节的树突和棘的发生。