Offret G, Pouliquen Y, Renard G
Klin Monbl Augenheilkd. 1977 Jun;170(6):796-803.
Studying the various stages of Fuchs' endothelial dystrophy with transmission and surface electronmicroscopy makes the dystrophic and degenerative changes in the endothelial and Descemet's membrane visible: dystrophic changes by the formation of tuberosities, whose structure is very similar to that Descemet's membrane, and degenerative changes by reduction in the number of endothelial cells through destruction of the intercellular connections and through cell necrosis. The second stage is the reformation of the structure by fibroblastic cells. The dystrophic cells lead to the formation of a fibrillary tissue between the cells and the tuberosity-laden Descemet's membrane, which is different from the primary structure of this tissue. The origin of these cells is unknown.
通过透射电子显微镜和表面电子显微镜研究富克斯内皮营养不良的各个阶段，可以看到内皮细胞和后弹力层的营养不良性和退行性变化：通过形成结节状突起产生营养不良性变化，其结构与后弹力层非常相似；通过细胞间连接的破坏和细胞坏死导致内皮细胞数量减少产生退行性变化。第二阶段是成纤维细胞对结构的重塑。营养不良的细胞导致在细胞与充满结节的后弹力层之间形成纤维组织，这与该组织的原始结构不同。这些细胞的起源尚不清楚。
