Department of Interventional Cardiology, Cardiovascular Hospital and Claude Bernard University and INSERM Unit 1060 CARMEN, Lyon, France.
Department of Interventional Cardiology, Cardiovascular Hospital and Claude Bernard University and INSERM Unit 1060 CARMEN, Lyon, France.
Int J Cardiol. 2019 Jan 1;274:71-73. doi: 10.1016/j.ijcard.2018.09.041. Epub 2018 Sep 13.
Initial proximal optimization technique (POT) in provisional stenting improves global malapposition, side-branch (SB) obstruction (SBO) and conservation of arterial circularity. The specific mechanical effects of a final POT sequence concluding the main provisional stenting techniques, on the other hand, are unknown.
Synergy™ stents were implanted on fractal coronary bifurcation bench models using the main provisional stenting techniques (n = 5 per group): kissing-balloon inflation (KBI), snuggle, and rePOT (initial POT + SB inflation + final POT). Final results were quantified on 2D and 3D OCT before and after final POT. Whichever the technique, final POT significantly decreased global malapposition (from 7.6 ± 5.3% to 2.2 ± 2.5%, p < 0.05) and proximal elliptic deformation (from 1.15 ± 0.07 to 1.09 ± 0.04, p < 0.05), without impact on SBO (from 11.5 ± 9.6% to 12.9 ± 10.6%, NS). However, final POT failed to completely correct the elliptic deformation induced by balloon juxtaposition during the KBI and snuggle techniques, with final elliptic ratios of 1.11 ± 0.03 and 1.11 ± 0.04 respectively, significantly higher than with the complete rePOT sequence: 1.05 ± 0.02 (p < 0.05).
Like initial POT, final POT is recommended whatever the provisional stenting technique used. However, final POT fails to completely correct all proximal elliptic deformation associated with "kissing-like" techniques, in contrast to results with the rePOT sequence.
在临时支架置入术中采用初始近端优化技术(POT)可改善整体贴壁不良、边支(SB)阻塞(SBO)和保持动脉圆度。另一方面,完成临时支架置入术的最后 POT 序列的具体力学效应尚不清楚。
在分叉冠状动脉分岔模型上采用主要临时支架置入术(每组 5 个支架)置入 Synergy™支架:球囊对吻扩张(KBI)、贴靠、再 POT(初始 POT+SB 扩张+最终 POT)。在最后 POT 前后,采用二维和三维 OCT 定量分析最终结果。无论采用何种技术,最终 POT 均可显著降低整体贴壁不良(从 7.6±5.3%降至 2.2±2.5%,p<0.05)和近端椭圆变形(从 1.15±0.07 降至 1.09±0.04,p<0.05),但对 SBO 无影响(从 11.5±9.6%增至 12.9±10.6%,NS)。然而,最终 POT 无法完全纠正 KBI 和贴靠技术中球囊并列引起的椭圆变形,最终椭圆比分别为 1.11±0.03 和 1.11±0.04,显著高于完整的再 POT 序列:1.05±0.02(p<0.05)。
与初始 POT 一样,无论采用何种临时支架置入技术,均推荐使用最终 POT。然而,与再 POT 序列相比,最终 POT 无法完全纠正与“吻-like”技术相关的所有近端椭圆变形。