Alalawi Rahmah, Yasmeen Nusrath
J Perianesth Nurs. 2018 Oct;33(5):732-740. doi: 10.1016/j.jopan.2017.04.009. Epub 2017 Sep 12.
The incidence of postoperative cognitive dysfunction (POCD) remains a relatively common complication in the elderly following surgery. Use of anesthesia for surgery might precipitate certain cognitive alterations. The purpose of this review is to address the impact of two volatile anesthetic agents, desflurane and sevoflurane, on POCD.
The focus of this review was on postoperative recovery and complications using two anesthetic agents.
Several databases including PubMed and Cochrane were searched from the date of inception. The search words POCD, elderly, general anesthetics, desflurane, and sevoflurane were used and the search was limited to human, randomized clinical trials, and English.
The findings show no difference in the emergence time between sevoflurane and desflurane and the incidence of POCD.
No definitive conclusion can be drawn about the type of anesthetic used and its relation to occurrence of POCD. However, the information presented is crucial, which can help to improve anesthetic usage and patient safety.
术后认知功能障碍(POCD)的发生率在老年患者术后仍是一种相对常见的并发症。手术麻醉的使用可能会引发某些认知改变。本综述的目的是探讨两种挥发性麻醉剂地氟烷和七氟烷对POCD的影响。
本综述的重点是使用两种麻醉剂后的术后恢复及并发症情况。
从数据库建立之日起检索包括PubMed和Cochrane在内的多个数据库。使用了“POCD”“老年”“全身麻醉剂”“地氟烷”和“七氟烷”等检索词,检索仅限于人类、随机临床试验及英文文献。
结果显示七氟烷和地氟烷在苏醒时间及POCD发生率方面无差异。
关于所使用麻醉剂的类型及其与POCD发生的关系,无法得出明确结论。然而,所提供的信息至关重要,有助于改善麻醉的使用及患者安全。