Wang Cong, Li Liqin, Xu Hongyu, Lv Hongliu, Zhang Houzhong
Pharmazie. 2019 Apr 1;74(4):201-205. doi: 10.1691/ph.2019.8935.
: We conducted a meta-analysis to evaluate different indexes of the postoperative resuscitation period in elderly patients who received desflurane-remifentanil or sevoflurane-remifentanil. : A systematic search of the PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure and Wanfang databases for randomized controlled trials (RCTs) of elderly patients who received desflurane-remifentanil or sevoflurane-remifentanil was conducted. Extracted data were analysed using RevMan version 5.3. s: Six studies involving 336 patients were included. Results indicated that the time to open eyes, time to extubation and time to orientation were faster in the desflurane group than in the sevoflurane group (<0.05). There was no significant difference in the time of discharging from the recovery room between the desflurane and sevoflurane groups (>0.05). The incidence of vomiting and agitation was lower in the desflurane group than in the sevoflurane group (<0.05). No significant difference of hypotension and hypertension was found (>0.05). : Elderly patients who received desflurane-remifentanil exhibited faster recovery than those who received sevoflurane-remifentanil.
我们进行了一项荟萃分析，以评估接受地氟醚-瑞芬太尼或七氟醚-瑞芬太尼的老年患者术后复苏期的不同指标。
对PubMed、Embase、Cochrane图书馆、中国知网和万方数据库进行系统检索，以查找接受地氟醚-瑞芬太尼或七氟醚-瑞芬太尼的老年患者的随机对照试验（RCT）。使用RevMan 5.3版对提取的数据进行分析。
纳入了6项涉及336例患者的研究。结果表明，地氟醚组的睁眼时间、拔管时间和定向时间比七氟醚组更快（<0.05）。地氟醚组和七氟醚组之间从恢复室出院的时间没有显著差异（>0.05）。地氟醚组的呕吐和躁动发生率低于七氟醚组（<0.05）。未发现低血压和高血压有显著差异（>0.05）。
接受地氟醚-瑞芬太尼的老年患者比接受七氟醚-瑞芬太尼的患者恢复得更快。
