Universidade de Santa Cruz, Departamento de Cirurgia, Santa Cruz, RS, Brazil.
Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil; Universidade Federal de Ciências da Saúde de Porto Alegre, Laboratório de Pesquisa em Imagens Médicas, Porto Alegre, RS, Brazil.
J Pediatr (Rio J). 2020 Jan-Feb;96(1):92-99. doi: 10.1016/j.jped.2018.07.010. Epub 2018 Sep 17.
To evaluate the feasibility of using ultra-low-dose computed tomography of the chest with iterative reconstruction without anesthesia for assessment of pulmonary diseases in children.
This prospective study enrolled 86 consecutive pediatric patients (ranging from 1 month to 18 years) that underwent ultra-low-dose computed tomography due to suspicion of pulmonary diseases, without anesthesia and contrast. Parameters used were: 80kVp; 15-30mA; acquisition time, 0.5s; and pitch, 1.375. The adaptive statistical iterative reconstruction technique was used. Subjective visual evaluation and quantitative assessment of image quality were done using a 5-point scale in 12 different structures of the chest.
Mean age was 66 months (interquartile range, 16-147). Final diagnosis was performed in all exams, and 44 (51.2%) were diagnosed with cystic fibrosis, 27 (31.4%) with bronchiolitis obliterans, and 15 (17.4%) with congenital pulmonary airways malformations. Diagnostic quality was achieved in 98.9%, of which 82.6% were considered excellent and 16.3% were slightly blurred but did not interfere with image evaluation. Only one case (1.2%) presented moderate blurring that slightly compromised the image, and previous examinations demonstrated findings compatible with bronchiolitis obliterans. Mean effective radiation dose was 0.39±0.15mSv. Percentages of images with motion artifacts were 0.3% for cystic fibrosis, 1.3% for bronchiolitis obliterans, and 1.1% for congenital pulmonary airways malformations.
Chest ultra-low-dose computed tomography without sedation or anesthesia delivering a sub-millisievert dose can provide image quality to allow identification of common pulmonary anatomy and diseases.
评估在不进行麻醉的情况下使用超低剂量胸部 CT 进行迭代重建以评估儿童肺部疾病的可行性。
本前瞻性研究纳入了 86 例连续的儿科患者(年龄 1 个月至 18 岁),因怀疑患有肺部疾病而接受了超低剂量 CT 检查,未进行麻醉和造影。使用的参数为:80kVp;15-30mA;采集时间为 0.5s;螺距为 1.375。使用自适应统计迭代重建技术。采用 5 分制对胸部 12 个不同结构进行主观视觉评估和图像质量的定量评估。
平均年龄为 66 个月(四分位距,16-147)。所有检查均做出了最终诊断,其中 44 例(51.2%)诊断为囊性纤维化,27 例(31.4%)诊断为闭塞性细支气管炎,15 例(17.4%)诊断为先天性肺气道畸形。诊断质量达到 98.9%,其中 82.6%被认为是极好的,16.3%稍微模糊但不影响图像评估。只有 1 例(1.2%)表现为中度模糊,稍微影响图像质量,而之前的检查结果显示与闭塞性细支气管炎相符。平均有效辐射剂量为 0.39±0.15mSv。囊性纤维化、闭塞性细支气管炎和先天性肺气道畸形的运动伪影图像比例分别为 0.3%、1.3%和 1.1%。
不进行镇静或麻醉的胸部超低剂量 CT 可提供足以识别常见肺部解剖结构和疾病的图像质量,且剂量可低至亚毫希沃特。