泰勒氏病毒基因组与脑心肌炎病毒（原型心病毒）的基因组密切相关。
Theiler's virus genome is closely related to that of encephalomyocarditis virus, the prototype cardiovirus.
作者信息
Ozden S, Tangy F, Chamorro M, Brahic M
出版信息
J Virol. 1986 Dec;60(3):1163-5. doi: 10.1128/JVI.60.3.1163-1165.1986.
Abstract
Theiler's virus causes a persistent demyelinating infection of the mouse central nervous system. Our study of the molecular mechanism of persistence led us to sequence 1925 nucleotides located at the 3' end of the viral genome. We observed extensive homologies between this region and the corresponding region of encephalomyocarditis virus, the prototype cardiovirus, and only some homologies with the 3' ends of foot-and-mouth disease virus, rhinovirus, and poliovirus genomes.
摘要
泰勒病毒会引发小鼠中枢神经系统持续性脱髓鞘感染。我们对病毒持续性分子机制的研究促使我们对位于病毒基因组3'端的1925个核苷酸进行测序。我们观察到该区域与原型心病毒脑心肌炎病毒的相应区域存在广泛的同源性，而与口蹄疫病毒、鼻病毒和脊髓灰质炎病毒基因组的3'端仅有一些同源性。
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Theiler's virus genome is closely related to that of encephalomyocarditis virus, the prototype cardiovirus.泰勒氏病毒基因组与脑心肌炎病毒（原型心病毒）的基因组密切相关。
J Virol. 1986 Dec;60(3):1163-5. doi: 10.1128/JVI.60.3.1163-1165.1986.
2
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