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胎儿手术:麻醉影响与策略管理。

Foetal surgery: Anaesthetic implications and strategic management.

作者信息

Kodali Bhavani Shankar, Bharadwaj Shobana

机构信息

University of Maryland Medical Center, University of Maryland, Baltimore, Maryland, USA.

出版信息

Indian J Anaesth. 2018 Sep;62(9):717-723. doi: 10.4103/ija.IJA_551_18.

Abstract

Intrauterine surgery is being performed with increasing frequency. Correction of foetal anomalies can result in normal growth of foetus and a healthier baby at delivery. Intrauterine surgery can also improve the survival of babies who would have otherwise died at delivery, or in the neonatal period. There are three commonly used approaches to correct foetal anomalies: open surgery, where the foetus is exposed through hysterotomy; percutaneous approach, where needle or foetoscope is inserted through the abdominal wall and the uterine wall; finally, intrapartum treatment (EXIT) surgery, where the intervention is performed on the baby before terminating the maternal umbilical support to the baby. Anaesthetic management of the mother and the foetus requires good understanding of maternal physiology, foetal physiology, and pharmacological and surgical implications to the foetus. Uterine relaxation is a critical requisite for open foetal procedures and EXIT procedures. General anaesthesia and/or regional anaesthesia can be used successfully depending on the nature of foetal intervention. Foetal surgery poses complications not only to the foetus but also to the mother. Therefore, the decision for undertaking foetal surgery should always consider the risk to the mother versus benefit to the foetus.

摘要

宫内手术的实施频率越来越高。胎儿畸形的矫正可使胎儿正常生长,并在分娩时生出更健康的婴儿。宫内手术还可提高那些否则会在分娩时或新生儿期死亡的婴儿的存活率。有三种常用的矫正胎儿畸形的方法:开放性手术,即通过子宫切开术暴露胎儿;经皮方法,即通过腹壁和子宫壁插入针或胎儿镜;最后是产时治疗(EXIT)手术,即在终止母亲对婴儿的脐部支持之前对婴儿进行干预。对母亲和胎儿的麻醉管理需要充分了解母体生理学、胎儿生理学以及对胎儿的药理学和手术影响。子宫松弛是开放性胎儿手术和EXIT手术的关键必要条件。根据胎儿干预的性质,全身麻醉和/或区域麻醉均可成功使用。胎儿手术不仅会给胎儿带来并发症,也会给母亲带来并发症。因此,决定进行胎儿手术时应始终权衡对母亲的风险与对胎儿的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2de5/6144553/0289b8b9961e/IJA-62-717-g006.jpg

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