Kanesa-Thasan Riti, Cox Mougnyan, Patel Manisha, Curtis Brian, Hurst Robert W, Kung David, Flanders Adam E
1 Department of Radiology, Thomas Jefferson University Hospital, USA.
2 Department of Radiology, Hospital of the University of Pennsylvania, USA.
Neuroradiol J. 2018 Dec;31(6):572-577. doi: 10.1177/1971400918800468. Epub 2018 Sep 21.
Providing a fast and accurate diagnosis of acute large-vessel occlusion on computed tomography angiograms (CTAs) is essential for timely intervention and good stroke outcomes. However, the detection and appropriate management of incidental findings are also important parts of any clinical radiology practice and can greatly affect patient care. The intricate anatomy covered by CTAs of the head and neck coupled with the time pressures of acute stroke diagnosis creates an environment in which unrelated, important findings can potentially be missed. The purpose of our study was to document clinically actionable incidental findings on CTA in 225 patients undergoing acute stroke intervention. After institutional review board approval, a retrospective six-year review of CTAs of the head and neck in patients undergoing acute stroke intervention was performed for actionable incidental vascular and nonvascular findings. A total of 225 patients undergoing acute stroke intervention with documented intracranial large-vessel occlusion on CTAs were consecutively enrolled in the study. Incidental vascular findings were identified in 17 of 225 patients (7.5%, 95% confidence interval 5% to 12%). Previously unreported aneurysms ranging from 2 mm to 10 mm in size represented 18 of 19 vascular findings in these patients. Incidental nonvascular findings were identified in 32 patients (14%, 95% confidence interval 5% to 12%). These included malpositioned support lines and tubes; pneumothorax; interstitial lung disease; newly diagnosed metastatic disease; nasopharyngeal, parotid, and pituitary masses; and cervical spine compression fractures. CTAs of the head and neck in patients undergoing acute stroke intervention contain a relatively high frequency of vascular and nonvascular incidental findings requiring further follow-up, and therefore should be evaluated carefully and systematically.
在计算机断层血管造影(CTA)上快速准确地诊断急性大血管闭塞对于及时干预和良好的卒中预后至关重要。然而,偶然发现的检测和适当管理也是任何临床放射学实践的重要组成部分,并且会极大地影响患者护理。头颈部CTA所涵盖的复杂解剖结构,加上急性卒中诊断的时间压力,营造了一个可能遗漏不相关但重要发现的环境。我们研究的目的是记录225例接受急性卒中干预患者CTA上具有临床可处理性的偶然发现。经机构审查委员会批准,对接受急性卒中干预患者的头颈部CTA进行了为期六年的回顾性研究,以寻找可处理的偶然血管和非血管发现。共有225例接受急性卒中干预且CTA记录有颅内大血管闭塞的患者连续纳入该研究。225例患者中有17例(7.5%,95%置信区间5%至12%)发现了偶然血管发现。这些患者中,19处血管发现中有18处为大小从2毫米至10毫米不等的既往未报告的动脉瘤。32例患者(14%,95%置信区间5%至12%)发现了偶然非血管发现。这些发现包括支撑线和导管位置不当;气胸;间质性肺疾病;新诊断的转移性疾病;鼻咽、腮腺和垂体肿块;以及颈椎压缩性骨折。接受急性卒中干预患者的头颈部CTA包含相对较高频率的需要进一步随访的血管和非血管偶然发现,因此应仔细且系统地进行评估。