支气管刷检与支气管活检：肺癌诊断准确性及细胞分型可靠性的比较
Bronchial brushing and bronchial biopsy: comparison of diagnostic accuracy and cell typing reliability in lung cancer.
作者信息
Matsuda M, Horai T, Nakamura S, Nishio H, Sakuma T, Ikegami H, Tateishi R
出版信息
Thorax. 1986 Jun;41(6):475-8. doi: 10.1136/thx.41.6.475.
A total of 443 patients with lung cancer underwent brush and forceps biopsy through a fibreoptic bronchoscope. The biopsy was taken from the area of suspected malignancy which had been brushed. Of 443 patients, 400 (90.3%) showed positive results on brushing and 287 (64.8%) on biopsy. A combination of both techniques yielded the highest percentage of positive diagnosis (93.7%). Histologically, there was a high incidence of positive diagnosis for squamous and small cell carcinoma. One hundred and three (83.7%) of 123 specimens obtained by brushing and 75 (81.5%) of 92 specimens obtained by biopsy agreed with the cell type found in the surgical or necropsy specimen. Cell typing accuracy was higher in squamous and in small cell carcinoma in both techniques. As the cell typing accuracy of the two methods is similar, the results obtained by both techniques should be taken into consideration in the management of individual cases of lung cancer.
共有443例肺癌患者通过纤维支气管镜进行了刷检和钳取活检。活检取自刷检过的疑似恶性病变区域。443例患者中，400例（90.3%）刷检结果为阳性，287例（64.8%）活检结果为阳性。两种技术联合使用时阳性诊断率最高（93.7%）。组织学上，鳞状细胞癌和小细胞癌的阳性诊断率较高。刷检获得的123份标本中有103份（83.7%），活检获得的92份标本中有75份（81.5%）与手术或尸检标本中发现的细胞类型一致。在两种技术中，鳞状细胞癌和小细胞癌的细胞分型准确性都较高。由于两种方法的细胞分型准确性相似，在肺癌个体病例的管理中应同时考虑两种技术所获得的结果。
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