Sadeghi Shayan, Azaïs Maxime, Ghannoum Julien
Department of Stomatology, University of Montreal Hospital Center, Montreal, QC, Canada.
Department of Oral and Maxillofacial Surgery, Thunder Bay Regional Health Sciences Centre, Thunder Bay, ON, Canada.
Head Neck Pathol. 2019 Sep;13(3):327-330. doi: 10.1007/s12105-018-0966-7. Epub 2018 Sep 22.
Cervicofacial actinomycosis is a common form of Actinomyces infection. However, the latter seldom occurs in the tongue. We present a case of a 66 year-old man with macroglossia caused by actinomycosis of the tongue. Radiographic features were compatible with a chronic inflammatory disease. Biopsies revealed granulomas containing giant cells and Gram positive bacterial clusters consistent with actinomycosis. The patient was treated with a 22 week course of antibiotics. Imaging showed a notable improvement in the extent of the lesions 1 year later. The patient was asymptomatic and in good condition during his second year follow-up. Diagnosis of actinomycosis of the tongue can prove to be challenging because of the non-specific nature of its symptoms, clinical signs, and radiographic features. Isolation of Actinomyces sp. is an added diagnostic hurdle, because of its fastidious nature.
颈面部放线菌病是放线菌感染的常见形式。然而，后者很少发生于舌部。我们报告一例66岁男性因舌部放线菌病导致巨舌症的病例。影像学特征与慢性炎症性疾病相符。活检显示肉芽肿内含有巨细胞和革兰氏阳性菌簇，符合放线菌病表现。该患者接受了为期22周的抗生素治疗。1年后影像学检查显示病变范围有显著改善。在第二年的随访中，患者无症状且状况良好。由于舌部放线菌病的症状、临床体征及影像学特征均不具有特异性，其诊断可能具有挑战性。由于放线菌属的苛求特性，对其进行分离培养是另一个诊断障碍。
