Capodiferro Saverio, Limongelli Luisa, Favia Gianfranco
Department of Interdisciplinary Medicine, University of Bari Aldo Moro, Piazza G. Cesare, 11, 70124 Bari, Italy.
Medicina (Kaunas). 2021 Mar 16;57(3):271. doi: 10.3390/medicina57030271.
Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral cavity and, more generally, the soft and hard tissues of the head and neck as primary or secondary localization. Primary onset in the oral cavity of both pediatric and adult diseases usually represents a true challenge for clinicians; their precocious detection is often difficult and requires a wide knowledge but surely results in the early diagnosis and therapy onset with an overall better prognosis and clinical outcomes. In the current paper, as for the topic of the current Special Issue, the authors present an overview on the most frequent clinical manifestations at the oral and maxillo-facial district of systemic disease.
许多全身性（感染性、遗传性、自身免疫性、肿瘤性）疾病可能累及口腔，更广泛地说，累及头颈部的软硬组织，作为原发或继发部位。儿科和成人疾病在口腔的原发性发病通常对临床医生来说是一个真正的挑战；它们的早期检测往往很困难，需要广泛的知识，但肯定会带来早期诊断和治疗，从而总体上有更好的预后和临床结果。在当前的论文中，就当前特刊的主题而言，作者概述了全身性疾病在口腔颌面区最常见的临床表现。
