Hasegawa Hitoshi
Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Methods Mol Biol. 2018;1868:235-241. doi: 10.1007/978-1-4939-8802-0_24.
Randomized controlled trials are commonly designed to compare the effectiveness of treatments in rheumatoid arthritis (RA). In a clinical trial (intervention study), researchers apply interventions or preventive services to patients and examine outcomes. Clinical trial design consists of the following categories: choice of intervention, selection of patients, informed consent, baseline measurement, bank specimens, randomized allocation and blinding, and outcome measurements. Here, we discuss the design of clinical trials for RA.
随机对照试验通常旨在比较类风湿性关节炎（RA）治疗方法的有效性。在临床试验（干预性研究）中，研究人员对患者实施干预措施或预防性服务，并检查结果。临床试验设计包括以下几类：干预措施的选择、患者的选择、知情同意、基线测量、样本储存、随机分配和盲法以及结果测量。在此，我们讨论类风湿性关节炎的临床试验设计。
