Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Methods Mol Biol. 2024;2766:317-324. doi: 10.1007/978-1-0716-3682-4_32.
Randomized controlled trials are commonly designed to compare the effectiveness of treatments in rheumatoid arthritis (RA). In a clinical trial (intervention study), researchers apply interventions or preventive services to patients and examine outcomes. Clinical trial design consists of the following categories: choice of intervention and control, selection of patients, informed consent, baseline measurement, bank specimens, randomized allocation and blinding, and outcome measurements. Here, we discuss the design of clinical trials for RA.
随机对照试验常用于比较类风湿关节炎 (RA) 治疗方法的有效性。在临床试验（干预研究）中，研究人员将干预或预防措施应用于患者，并检查结果。临床试验设计包括以下类别：干预和对照的选择、患者选择、知情同意、基线测量、标本库、随机分配和盲法、以及结果测量。在这里，我们讨论 RA 的临床试验设计。
