Lee Hyo Jeong, Park Hong Souk, Moon Hyun Im, Yoon Seo Yeon
Department of Rehabilitation Medicine, Bundang Jesaeng Hospital, Seongnam-si, Korea.
J Ultrasound Med. 2019 Mar;38(3):725-731. doi: 10.1002/jum.14758. Epub 2018 Sep 23.
To compare the efficacy of a conventional fluoroscopy-guided epidural nerve block and an ultrasound (US)-guided intercostal nerve block in patients with thoracic herpes zoster (HZ).
This work was a comparative study of 38 patients with thoracic HZ pain and a chest wall herpetic eruption, aged 18 years or older, with pain intensity of 5 or greater on a numeric rating scale (NRS) for less than a 1-month duration. Patients were consecutively enrolled and assigned to 2 groups in which the intervention was either the US-guided intercostal nerve block or the fluoroscopy-guided epidural nerve block approach with the addition of a 5-mL mix of 2.5 mg of dexamethasone plus 0.5% lidocaine. The primary outcome measure was the NRS score reduction for the pain. Secondary outcomes included the duration of treatment, number of repeated injections until the final visit, and proportion of patients with pain relief after the first and final visits.
All patients within both intervention groups showed significant pain relief on the NRS at the final follow-up point (P < .05). There was no significant difference in the mean value of NRS improvement based on the intervention type. There was also no statistically significant difference in the duration of treatment and the frequency of injection for pain relief.
These findings showed that both the US-guided intercostal nerve block and the fluoroscopy-guided epidural nerve block were effective in patients with thoracic HZ. Compared data showed no significant differences in the pain reduction, duration of treatment, and frequency of injection. The US-guided intercostal nerve block, which is more accessible than the fluoroscopy-guided epidural nerve block, might be an alternative option for thoracic HZ.
比较传统透视引导下硬膜外神经阻滞与超声引导下肋间神经阻滞对胸部带状疱疹(HZ)患者的疗效。
本研究为一项对比研究,纳入38例年龄≥18岁、胸部HZ疼痛且伴有胸壁疱疹疹出、疼痛强度在数字评分量表(NRS)上为5分及以上且持续时间小于1个月的患者。患者连续入组并分为2组,干预措施分别为超声引导下肋间神经阻滞或透视引导下硬膜外神经阻滞,同时添加2.5 mg地塞米松与0.5%利多卡因的5 mL混合液。主要结局指标为疼痛的NRS评分降低情况。次要结局指标包括治疗持续时间、直至最后一次就诊时的重复注射次数,以及首次和最后一次就诊后疼痛缓解的患者比例。
两个干预组的所有患者在最终随访时NRS评分均显著降低(P < 0.05)。基于干预类型的NRS改善平均值无显著差异。治疗持续时间和缓解疼痛的注射频率也无统计学显著差异。
这些结果表明,超声引导下肋间神经阻滞和透视引导下硬膜外神经阻滞对胸部HZ患者均有效。对比数据显示,在疼痛减轻、治疗持续时间和注射频率方面无显著差异。超声引导下肋间神经阻滞比透视引导下硬膜外神经阻滞更容易实施,可能是胸部HZ的一种替代选择。