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[化疗引起的周围神经病变:症状学与流行病学]

[Chemotherapy-induced peripheral neuropathy: Symptomatology and epidemiology].

作者信息

Kerckhove Nicolas, Collin Aurore, Condé Sakhalé, Chaleteix Carine, Pezet Denis, Balayssac David, Guastella Virginie

机构信息

Délégation à la recherche clinique et à l'innovation, CHU de Clermont-Ferrand, université Clermont-Auvergne, NEURO-DOL, Inserm U1107, 2, rue Braga, 63100 Clermont-Ferrand, France.

Université Clermont-Auvergne, NEURO-DOL, Inserm U1107, 2, rue Braga, 63100 Clermont-Ferrand, France.

出版信息

Bull Cancer. 2018 Nov;105(11):1020-1032. doi: 10.1016/j.bulcan.2018.07.009. Epub 2018 Sep 20.

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is common with specific semiological characteristics. When CIPN appears, there are many difficulties in guaranteeing sustained treatment, especially with optimal protocol. Moreover, CIPN have bad repercussions on quality of life after cancer disease. In this article, we have achieved a current state of CIPN and try to report details about semiological characteristics and topography. We have also produced some epidemiological data. Nonetheless, we have not voluntarily introduced treatment because it will be the topic of further work.

摘要

化疗引起的周围神经病变(CIPN)很常见,具有特定的症状学特征。当CIPN出现时,保证持续治疗存在许多困难,尤其是采用最佳方案时。此外,CIPN对癌症疾病后的生活质量有不良影响。在本文中,我们阐述了CIPN的现状,并试图报告其症状学特征和部位的详细情况。我们还提供了一些流行病学数据。尽管如此,我们并未主动介绍治疗方法,因为这将是后续工作的主题。

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