东方蝾螈幼体和成体红色背斑中河豚毒素（TTX）水平的调查

An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt () Efts and Adults.

作者信息

Spicer Mackenzie M, Stokes Amber N, Chapman Trevor L, Brodie Edmund D, Brodie Edmund D, Gall Brian G

机构信息

Department of Pharmacology, The University of Iowa, Iowa City, Iowa 52242, USA.

Department of Biology, California State University, Bakersfield, CA 93311, USA.

出版信息

J Toxicol. 2018 Sep 2;2018:9196865. doi: 10.1155/2018/9196865. eCollection 2018.

DOI:10.1155/2018/9196865

PMID:30245715

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6139183/

Abstract

We investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt () efts and adults. Several other species, such as and have granular glands concentrated in brightly pigmented regions on the dorsum, and thus we hypothesized that the red dorsal spots of Eastern newts may also possess higher levels of TTX than the surrounding skin. We found no difference between the concentrations of TTX in the red spots as compared to neighboring skin lacking these spots in either efts or adults. However, efts with more red dorsal spots had elevated TTX levels relative to efts with fewer spots.

摘要

我们研究了东方蝾螈幼体和成体中含有和不含有红色背部斑点的皮肤切片中的河豚毒素（TTX）浓度。其他几种物种，如[此处原文缺失具体物种名称]和[此处原文缺失具体物种名称]，其颗粒腺集中在背部颜色鲜艳的区域，因此我们推测东方蝾螈的红色背部斑点可能也比周围皮肤含有更高水平的TTX。我们发现，在幼体或成体中，红色斑点处的TTX浓度与相邻无这些斑点的皮肤相比没有差异。然而，红色背部斑点较多的幼体相对于斑点较少的幼体，其TTX水平有所升高。