Wang Keran, Lin Haijiang, Li Lingling, Wu Qionghai, Shen Weiwei, Liu Xing, Gao Meiyang, Zhou Sujuan, Ding Yingying, He Na
a Department of Epidemiology, School of Public Health , Fudan University , Shanghai , People's Republic of China.
b Key Laboratory of Public Health Safety of Ministry of Education , Shanghai , People's Republic of China.
AIDS Care. 2019 Apr;31(4):513-518. doi: 10.1080/09540121.2018.1524110. Epub 2018 Sep 24.
This retrospective cohort study was conducted from January 2009 to July 2016 to explore the occurrence and risk factors of self-reported fatigue within the first 6 months after receiving antiretroviral treatment (ART) among patients living with HIV in Taizhou City of Zhejiang province, Eastern China. In total, 1163 HIV-infected patients with a median follow-up duration of 27.8 months were included in the analysis. Among them, 261 (22.4%) reported fatigue within the first 6 months after ART. In the multivariable logistic regression analysis, self-reported fatigue within the first 6 months after ART was negatively associated with junior middle-school education or above, baseline CD4 cell count of 200-349 and >350 cells/μL (vs < 200 cells/μL), overweight at baseline (vs normal weight) but positively associated with ≥50 years old at initiation of ART (vs <30 years old), underweight at baseline, use of efavirenz (EFV) in the first-line regimen. Our data suggest that earlier initiation of ART and higher body mass index are preferred to restore the energy of HIV-infected patients with the EFV use in the era of ART in China.
