Aydinlar Elif Ilgaz, Dikmen Pinar Yalinay, Kocak Muge, Baykan Nigar, Seymen Nogayhan, Ozek Memet Metin
Department of Neurology, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Departments of Neurology.
J Clin Neurophysiol. 2019 Jan;36(1):60-66. doi: 10.1097/WNP.0000000000000523.
The aim of this single-center prospective cohort study is to record reliable transcranial motor-evoked potentials (TcMEPs) and to determine their thresholds under inhalational anesthesia in infants undergoing spine and spinal cord surgery.
A total of 15 infants (age <12 months) with mean (SD) months: 5.82 ± 3.45 were included. The entry criteria were that the child should be no older than 1 year of age and undergoing a surgical procedure at the conus-cauda region. The patients were monitored with motor-evoked potentials (TcMEPs) and bulbocavernosus reflex.
Transcranial motor-evoked potentials were recorded in all the patients in both upper and lower extremities in one muscle at least. All patients were monitored with a mean TcMEP threshold of 488.46 ± 99.76 V (range 310-740 V). The lowest threshold of TcMEPs was used to record the musculus abductor pollicis brevis mean of 315.15 ± 126.95 V (range 140-690 V) and the highest for musculus sphincter ani mean of 444.17 ± 138.54 V (range 206-700 V).
Intraoperative neuromonitoring for spine and spinal cord procedures of the infant population requires higher TcMEP thresholds and train count. Most patients aged older than 6 months require significantly lower TcMEPs.
本单中心前瞻性队列研究的目的是记录可靠的经颅运动诱发电位(TcMEPs),并确定在接受脊柱和脊髓手术的婴儿吸入麻醉下其阈值。
共纳入15例年龄小于12个月的婴儿,平均(标准差)月龄为5.82±3.45个月。纳入标准为年龄不超过1岁且正在进行圆锥马尾区域手术的儿童。对患者进行运动诱发电位(TcMEPs)和球海绵体反射监测。
所有患者至少在一块肌肉的上下肢均记录到经颅运动诱发电位。所有患者的TcMEP平均阈值为488.46±99.76V(范围310 - 740V)。记录到的TcMEPs最低阈值用于记录拇短展肌,平均为315.15±126.95V(范围140 - 690V),最高阈值用于记录肛门括约肌,平均为444.17±138.54V(范围206 - 700V)。
婴儿人群脊柱和脊髓手术的术中神经监测需要更高的TcMEP阈值和电刺激次数。大多数6个月以上的患者所需的TcMEPs显著更低。