开展研究以推动政策变革：马拉维一项比较髓内钉固定术与骨牵引术的多中心成本效益分析设计

Developing Research to Change Policy: Design of a Multicenter Cost-Effectiveness Analysis Comparing Intramedullary Nailing to Skeletal Traction in Malawi.

作者信息

Lau Brian C, Wu Hao-Hua, Mustafa Mohammed, Ibrahim John, Conway Devin, Agarwal-Harding Kiran, Shearer David W, Chokotho Linda

机构信息

Orthopaedic Trauma Institute, Institute for Global Orthopaedics and Traumatology, Department of Orthopaedic Surgery, University of California, San Francisco, Zuckerberg San Francisco General Hospital, San Francisco, CA.

Tulane University School of Medicine, New Orleans, LA.

出版信息

J Orthop Trauma. 2018 Oct;32 Suppl 7:S52-S57. doi: 10.1097/BOT.0000000000001299.

DOI:10.1097/BOT.0000000000001299

PMID:30247402

Abstract

INTRODUCTION

The purpose of our study is to prospectively evaluate the cost effectiveness of intramedullary nailing compared with skeletal traction in a resource-limited setting where traction remains the most common definitive treatment.

METHODS

This multicenter, prospective multicenter investigation was conducted in Malawi at 2 central hospitals and 3 district hospitals. The project was divided into phases. In phase 1, the EuroQol-5D and SMFA were translated and validated in Chichewa. In phase 2, adult patents with OTA/AO 32 femur shaft fractures were prospectively enrolled, and a comparison of quality of life and functional status was made. In phase 3, a cost-effectiveness analysis was performed between those treated with intramedullary nail and those treated with skeletal traction.

CONCLUSION

This study serves as an example of an economic study in orthopaedic surgery conducted in a resource-poor environment through academic collaboration.

摘要

引言

我们研究的目的是在资源有限的环境中前瞻性地评估髓内钉固定与骨牵引相比的成本效益，在这种环境中牵引仍然是最常见的确定性治疗方法。

方法

这项多中心、前瞻性多中心研究在马拉维的2家中心医院和3家地区医院进行。该项目分为几个阶段。在第1阶段，将欧洲五维健康量表（EuroQol-5D）和脊柱功能障碍量表（SMFA）翻译成奇切瓦语并进行验证。在第2阶段，前瞻性纳入患有OTA/AO 32型股骨干骨折的成年患者，并对生活质量和功能状态进行比较。在第3阶段，对接受髓内钉治疗的患者和接受骨牵引治疗的患者进行成本效益分析。