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采用简单起搏策略消融右侧希氏旁性室性心律失常。

Catheter ablation of right-sided para-Hisian ventricular arrhythmias using a simple pacing strategy.

机构信息

Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China; Guangdong Provincial Key Laboratory of Clinical Pharmacology, Guangdong General Hospital & Guangdong Academy of Medical Sciences, Guangzhou, China.

出版信息

Heart Rhythm. 2019 Mar;16(3):380-387. doi: 10.1016/j.hrthm.2018.09.015. Epub 2018 Sep 21.

Abstract

BACKGROUND

Ablation of para-Hisian ventricular arrhythmias (PH-VAs) is challenging because of the close relationship of the origin site and His bundle. Using pacing techniques to differentiate the near-field from far-field His activations, thereby avoiding atrioventricular block, has been reported in patients with para-Hisian accessory pathways.

OBJECTIVES

We applied the same pacing technique and 3-dimensional mapping to guide radiofrequency (RF) ablation in patients with right-sided PH-VAs and investigated the clinical outcome of such cases.

METHODS

Fourteen patients with right-sided PH-VAs were included in this study. The earliest activation sites were confirmed in the right ventricle on the 3-dimensional map. Pacing with different outputs was performed at the largest His potential site (P1) and the earliest activation site (P2). If the minimum His bundle-right bundle branch-captured output at P2 was higher than that at P1, RF ablation was performed at the site.

RESULTS

All the patients in this study had monomorphic premature ventricular contractions (PVCs) with a mean QRS duration of 118.3 ± 8.1 ms. A His-right bundle branch potential with an amplitude of 0.05 ± 0.02 mV was recorded at P2, with a mean distance of 5.97 ± 1.84 mm away from P1. PVCs were successfully eliminated in 13 of 14 patients (92.9%). One patient exhibited persistent right bundle branch block after ablation, and 1 recurrence of ablated PVCs occurred during a median follow-up period of 15 months.

CONCLUSION

Using a simple pacing technique to evaluate the safety of RF energy application led to a high success rate of RF catheter ablation of right-sided PH-VAs without atrioventricular block.

摘要

背景

由于起源部位与希氏束的密切关系,消融旁希氏区室性心律失常(PH-VAs)具有挑战性。已有研究报道,在存在旁希氏旁路的患者中,使用起搏技术来区分近场和远场希氏激活,从而避免房室传导阻滞。

目的

我们应用相同的起搏技术和 3 维标测指导右侧 PH-VAs 的射频(RF)消融,并研究了此类病例的临床结果。

方法

本研究纳入了 14 例右侧 PH-VAs 患者。在 3 维标测图上,首先确定右心室最早的激活部位。在最大希氏电位部位(P1)和最早激活部位(P2)进行不同输出的起搏。如果 P2 的最小希氏束-右束支夺获输出高于 P1,则在该部位行 RF 消融。

结果

本研究所有患者均表现为形态单一的室性期前收缩(PVCs),平均 QRS 波时限为 118.3±8.1 ms。在 P2 记录到一个希氏-右束支电位,幅度为 0.05±0.02 mV,距离 P1 的平均距离为 5.97±1.84 mm。14 例患者中有 13 例(92.9%)PVCs 成功消除。1 例患者消融后持续存在右束支阻滞,1 例患者在中位随访 15 个月时出现消融 PVCs 复发。

结论

应用一种简单的起搏技术评估 RF 能量应用的安全性,可使右侧 PH-VAs 的 RF 导管消融成功率高,且不伴房室传导阻滞。

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