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特发性三尖瓣环附近起源室性心律失常的心电图和电生理特征。

Electrocardiographic and electrophysiological characteristics of idiopathic ventricular arrhythmias originating from the vicinity of tricuspid annulus.

机构信息

Department of Cardiovasology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.

Department of Emergency, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.

出版信息

Sci Rep. 2021 Apr 21;11(1):8633. doi: 10.1038/s41598-021-88036-7.

Abstract

Electrocardiographic and electrophysiological characteristics of VAs originating from the vicinity of the TA are not fully understood. Hence, 104 patients (mean age 52.6 ± 17.9 years; 62 male) with VAs originating from the vicinity of the TA were enrolled. After electrophysiological evaluation and ablation, data were compared among those patients. The ECGs and the correction of the ECGs based on the long axis of the heart calculated from the chest X-Ray were also analyzed. VAs originating from the vicinity of TA had distinctive ECG characteristics that were useful for identifying the precise origin. Our localization algorithm adjusted by the angle between the cardiac long axis and the horizon was found to be accurate in predicting the exact ablation site in 92.3% (n = 96) cases. Logistic regression analysis showed fractionated electrograms, the magnitudes of the local atrial electrograms and a/V ratio were critical factors for successful ablation. Among the 104 patients with VAs, complete elimination could be achieved by RFCA in 96 patients (success rate 92.3%) during a follow-up period of 35.2 ± 19.6 months. This study suggests that the ablation site could be localized by ECG analysis adjusted by the angle between the cardiac long axis and the horizon. Fractionated electrograms, the magnitudes of the local atrial electrograms and a/V ratio were demonstrated to be critical factors for successful ablation.

摘要

VA 起源于主动脉旁的心电图和电生理特征尚未完全了解。因此,纳入了 104 名(平均年龄 52.6±17.9 岁;62 名男性)VA 起源于主动脉旁的患者。在进行电生理评估和消融后,对这些患者的数据进行了比较。还分析了心电图和根据胸部 X 光计算的心脏长轴校正的心电图。起源于主动脉旁的 VA 具有独特的心电图特征,有助于确定准确的起源。我们通过心脏长轴与地平线之间的夹角调整的定位算法,发现对于预测确切的消融部位准确率高达 92.3%(n=96)。Logistic 回归分析显示,碎裂电图、局部心房电图幅度和 a/V 比值是成功消融的关键因素。在 104 名 VA 患者中,96 名患者(成功率 92.3%)在 35.2±19.6 个月的随访期间可通过 RFCA 实现完全消除。本研究表明,通过与心脏长轴和地平线之间夹角校正的心电图分析可以定位消融部位。碎裂电图、局部心房电图幅度和 a/V 比值被证明是成功消融的关键因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f781/8060328/309a32810e3a/41598_2021_88036_Fig1_HTML.jpg

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