伊朗南部设拉子市孕妇沙眼衣原体和淋病奈瑟菌感染的流行情况及其新生儿出生时眼部定植情况。
Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae infections among pregnant women and eye colonization of their neonates at birth time, Shiraz, Southern Iran.
机构信息
Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Departments of Microbiology, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
出版信息
BMC Infect Dis. 2018 Sep 24;18(1):477. doi: 10.1186/s12879-018-3382-4.
BACKGROUND
Chlamydia trachomatis and Neisseria gonorrhoeae are the two common transmissible pathogens from pregnant women to their neonates. Given the lack of routine screening and treatment of pregnant women in some areas, the possibility of transmission rises. This study seeks to determine the prevalence of C. trachomatis and N. gonorrhoeae in the pregnant women with no clinical symptoms and the vertical transmission rate to their neonates.
METHODS
The study was conducted on endocervical and eye swab samples of 239 pregnant women and their neonates. Identification was based on PCR method.
RESULTS
The prevalence rates of C.trachomatis in women and neonates were 37/239 (15.5%) and 28/239 (11.7%), and for N. gonorrhoeae 3/239 (1.3%), 1/239 (0.4%), respectively. The vertical transmission rates to the neonates were 28/37(75.6%) for C. trachomatis and 1/3 for N. gonorrhoeae.
CONCLUSIONS
In the areas with a high prevalence of chlamydial or gonococcal infections, and in the absence of screening and treatment of the pregnant women, ocular prophylaxis with antibiotics is suggested as a part of routine neonatal care program for the prevention of chlamydial and gonococcal ophthalmia.
背景
沙眼衣原体和淋病奈瑟菌是两种常见的可从孕妇传播给新生儿的传染性病原体。由于某些地区缺乏对孕妇的常规筛查和治疗，传播的可能性增加。本研究旨在确定无临床症状的孕妇中沙眼衣原体和淋病奈瑟菌的流行率及其垂直传播给新生儿的比率。
方法
对 239 名孕妇及其新生儿的宫颈和眼拭子样本进行了研究。鉴定基于 PCR 方法。
结果
妇女和新生儿中沙眼衣原体的流行率分别为 37/239（15.5%）和 28/239（11.7%），淋病奈瑟菌的流行率分别为 3/239（1.3%）、1/239（0.4%）。沙眼衣原体向新生儿的垂直传播率为 28/37（75.6%），淋病奈瑟菌为 1/3。
结论
在沙眼衣原体或淋球菌感染流行率较高的地区，且孕妇未进行筛查和治疗的情况下，建议在常规新生儿护理方案中进行眼部抗生素预防，以预防沙眼衣原体和淋球菌性眼炎。
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