Vanidassane Ilavarasi, Mittal Abhenil, Kumar Chandan, Tanwar Pranay, Sahoo Ranjit Kumar, Batra Atul
Department of Medical Oncology, BRAIRCH, AIIMS, New Delhi, India.
Laboratory Oncology Unit, BRAIRCH, AIIMS, New Delhi, India.
BMJ Case Rep. 2018 Sep 23;2018:bcr-2018-226385. doi: 10.1136/bcr-2018-226385.
A 35-year-old man presented with a history of cough, haemoptysis, weight loss for 2 months along with ulceroproliferative lesions on the chin and the scalp. On evaluation he was found to have non-seminomatous germ cell tumour, stage 3 c, poor risk with Eastern Cooperative Oncology Group Performance Status of 4. The skin lesions were proven to be metastasis by fine-needle aspiration cytology. He showed significant improvement with a 3-day protocol of abbreviated etoposide and cisplatin chemotherapy and is planned for 4 cycles of VIP. This case describes an uncommon presentation of germ cell tumour in the form of skin metastasis with excellent response to chemotherapy.
一名35岁男性,有咳嗽、咯血、体重减轻2个月的病史,同时下巴和头皮有溃疡性增殖性病变。经评估,他被诊断为非精原细胞性生殖细胞肿瘤,3c期,高危,东部肿瘤协作组体能状态为4级。细针穿刺细胞学检查证实皮肤病变为转移灶。他接受了为期3天的依托泊苷和顺铂简化化疗方案,病情有显著改善,并计划进行4个周期的VIP化疗。本病例描述了生殖细胞肿瘤以皮肤转移的形式出现的罕见表现,对化疗有良好反应。