Peng Long, Tu Yi, Li Yong, Xiao Weidong
Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China.
Department of Pathology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China.
J Cancer Res Ther. 2018 Sep;14(Supplement):S796-S799. doi: 10.4103/0973-1482.183551.
Low-grade myofibroblastic sarcoma (LGMS) is a malignant tumor with myofibroblastic differentiation, which frequently occurs in the oral cavity and extremities. Here, we report a case of LGMS of the pancreas in a 44-year-old female presented to our hospital with recurrent upper abdominal pain. Computed tomography revealed a low-density solid tumor at the body of the pancreas. Distal pancreatectomy combined with splenectomy was performed. LGMS of the pancreas was diagnosed by the histological features together with immunohistochemical findings. The patient received adjuvant chemotherapy after surgery and remained asymptomatic for 5 years. Previous studies and our experience suggested that surgical excision with wide margins is the reasonable treatment of LGMS and adjuvant therapy may improve its prognosis.
低度恶性肌纤维母细胞肉瘤（LGMS）是一种具有肌纤维母细胞分化的恶性肿瘤，常发生于口腔和四肢。在此，我们报告一例44岁女性胰腺LGMS病例，该患者因反复上腹部疼痛前来我院就诊。计算机断层扫描显示胰腺体部有一个低密度实性肿瘤。行远端胰腺切除术联合脾切除术。通过组织学特征及免疫组化结果诊断为胰腺LGMS。患者术后接受辅助化疗，5年来一直无症状。既往研究及我们的经验表明，手术切缘足够宽是LGMS的合理治疗方法，辅助治疗可能改善其预后。
