Hansen Peter Møller, Hansen Kristoffer Lindskov, Pedersen Mads Møller, Lange Theis, Lönn Lars, Jensen Jørgen Arendt, Nielsen Michael Bachmann
Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark.
Ultrasound Int Open. 2018 Sep;4(3):E79-E84. doi: 10.1055/a-0637-2437. Epub 2018 Sep 18.
Atherosclerotic arteries are challenging to evaluate quantitatively using spectral Doppler ultrasound because of the turbulent flow conditions that occur in relation to the atherosclerotic stenoses. Vector velocity ultrasound is angle independent and provides flow information, which could potentially improve the diagnosis of arterial stenoses. The purpose of the study is to distinguish significant stenoses in the superficial femoral artery (> 50% diameter reduction) from non-significant stenoses based on velocity ratios derived from the commercially available vector velocity ultrasound technique Vector Flow Imaging (VFI).
Velocity ratios (intrastenotic blood flow velocity divided by pre- or poststenotic velocity) from a total of 16 atherosclerotic stenoses and plaques in the superficial femoral artery of 11 patients were obtained using VFI. The stenosis degree, expressed as percentage diameter reduction of the artery, was determined from digital subtraction angiography and compared to the velocity ratios.
A velocity ratio of 2.5 was found to distinguish clinically relevant stenoses with>50% diameter reduction from clinically non-relevant stenoses with<50% diameter reduction and the difference was statistically significant.
The study indicates that VFI is a potential future tool for the evaluation of arterial stenoses.
由于与动脉粥样硬化狭窄相关的湍流情况,使用频谱多普勒超声对动脉粥样硬化动脉进行定量评估具有挑战性。矢量速度超声与角度无关,并能提供血流信息,这可能会改善动脉狭窄的诊断。本研究的目的是基于从市售矢量速度超声技术矢量血流成像(VFI)获得的速度比,区分股浅动脉中显著狭窄(直径减少>50%)和非显著狭窄。
使用VFI获得了11例患者股浅动脉中总共16处动脉粥样硬化狭窄和斑块的速度比(狭窄内血流速度除以狭窄前或狭窄后速度)。通过数字减影血管造影确定以动脉直径减少百分比表示的狭窄程度,并与速度比进行比较。
发现速度比为2.5可区分直径减少>50%的临床相关狭窄和直径减少<50%的临床不相关狭窄,且差异具有统计学意义。
该研究表明VFI是未来评估动脉狭窄的一种潜在工具。