Johnson B J, Castro A E
J Am Vet Med Assoc. 1986 Nov 15;189(10):1345-7.
In an aviary housing 200 six-month-old canaries, 165 became ill and 145 died over a 6-week period from a disease initially characterized by lethargy, ruffled feathers, open-mouth breathing, and death in 2 to 3 days. Proliferative "pox-like" lesions around the eyes and mouth were not seen until the 4th week. At necropsy, initially affected birds had cloudy air sacs and patchy pneumonia. Histologically, the lungs had proliferative necrotizing bronchitis. Birds necropsied later had proliferative skin lesions and intracytoplasmic inclusions typical of poxvirus in the epidermis and airway epithelium. A virus was isolated from an organ pool of lung, air sac, liver, and skin of affected birds and was identified by electron microscopy as poxvirus.
在一个饲养着200只6个月大金丝雀的鸟舍中，在6周的时间里，有165只鸟生病，145只死亡，最初这种疾病的特征是嗜睡、羽毛蓬乱、张嘴呼吸，并在2至3天内死亡。直到第4周才出现眼睛和嘴巴周围的增殖性“痘样”病变。尸检时，最初受影响的鸟类气囊浑浊，有斑片状肺炎。组织学上，肺部有增殖性坏死性支气管炎。后来进行尸检的鸟类有增殖性皮肤病变，表皮和气道上皮有痘病毒特有的胞浆内包涵体。从患病鸟类的肺、气囊、肝脏和皮肤的器官池中分离出一种病毒，通过电子显微镜鉴定为痘病毒。
