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先天性门体分流手术减容后与健康对照相比的健康相关生活质量。

Health-related quality of life following surgical attenuation of congenital portosystemic shunts versus healthy controls.

作者信息

Bristow P, Lipscomb V, Kummeling A, Packer R, Gerrits H, Homan K, Ortiz V, Newson K, Tivers M

机构信息

Department of Veterinary Clinical Sciences, Royal Veterinary College, Hatfield, Herts, AL9 7TA, UK.

Faculty of Veterinary Medicine, Clinical Sciences of Companion Animals, Utrecht University, Utrecht, 3508, The Netherlands.

出版信息

J Small Anim Pract. 2019 Jan;60(1):21-26. doi: 10.1111/jsap.12927. Epub 2018 Sep 25.

Abstract

OBJECTIVES

To design a health-related quality of life questionnaire for dogs with congenital portosystemic shunts, use it in a cohort of dogs treated with suture attenuation and compare results with those obtained from a healthy control cohort.

MATERIALS AND METHODS

Data were collected from the hospital records of dogs treated with suture ligation of an intrahepatic or extrahepatic congenital portosystemic shunt at two referral centres. Owners were asked to complete a questionnaire assessing their dog's health-related quality of life preoperatively (retrospectively) and at the time of follow-up. Owners of control dogs also completed the questionnaire.

RESULTS

One hundred and twenty-eight dogs with congenital portosystemic shunts and 131 control dogs were recruited. Median follow-up time was 64 months (range 19.7 to 157.2). The median long-term health-related quality of life score was excellent for both intrahepatic and extrahpatic shunt cases and similar to that of control dogs. The long-term portosystemic shunt clinical sign scores for both intrahepatic and extrahepatic congenital portosystemic shunt dogs were significantly worse than the those of the control group.

CLINICAL SIGNIFICANCE

Suture attenuation of congenitial portosystemic shunts is associated with an excellent health-related quality of life score at long-term follow-up.

摘要

目的

为患有先天性门体分流的犬只设计一份与健康相关的生活质量问卷,将其应用于一组接受缝合减张治疗的犬只,并将结果与健康对照犬只组的结果进行比较。

材料与方法

从两个转诊中心接受肝内或肝外先天性门体分流缝合结扎治疗的犬只的医院记录中收集数据。要求犬主完成一份问卷,评估其犬只术前(回顾性)和随访时与健康相关的生活质量。对照犬只的主人也完成了问卷。

结果

招募了128只患有先天性门体分流的犬只和131只对照犬只。中位随访时间为64个月(范围19.7至157.2个月)。肝内和肝外分流病例的长期与健康相关的生活质量评分中位数均为优秀,且与对照犬只相似。肝内和肝外先天性门体分流犬只的长期门体分流临床体征评分均显著低于对照组。

临床意义

先天性门体分流的缝合减张在长期随访中与优秀的健康相关生活质量评分相关。

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