Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio, USA.
Potrero Scientific, LLC, San Francisco, California, USA.
Sci Data. 2018 Sep 25;5:180193. doi: 10.1038/sdata.2018.193.
Musculoskeletal extremities exhibit a multi-layer tissue structure that is composed of skin, fat, and muscle. Body composition and anthropometric measurements have been used to assess health status and build anatomically accurate biomechanical models of the limbs. However, comprehensive datasets inclusive of regional tissue anatomy and response under mechanical manipulation are missing. The goal of this study was to acquire and disseminate anatomical and mechanical data collected on extremities of the general population. An ultrasound system, instrumented with a load transducer, was used for in vivo characterization of skin, fat, and muscle thicknesses in the extremities of 100 subjects at unloaded (minimal force) and loaded (through indentation) states. For each subject, the unloaded and loaded state provided anatomic tissue layer measures and tissue indentation response for 48 and 8 regions, respectively. A publicly available web-based system has been used for data management and dissemination. This comprehensive database will provide the foundation for comparative studies in regional musculoskeletal composition and improve visual and haptic realism for computational models of the limbs.
四肢的肌肉骨骼系统具有多层次的组织结构，包括皮肤、脂肪和肌肉。人体成分和人体测量学的测量方法被用于评估健康状况，并构建四肢的解剖学精确生物力学模型。然而，目前还缺乏包括区域组织解剖结构和机械操作下的响应的综合数据集。本研究的目的是获取和传播一般人群四肢的解剖学和力学数据。使用带有负载传感器的超声系统对 100 名受试者的四肢在空载（最小力）和加载（通过压痕）状态下的皮肤、脂肪和肌肉厚度进行了体内特征描述。对于每个受试者，空载和加载状态分别提供了 48 个和 8 个区域的解剖组织层测量值和组织压痕响应。一个公开的基于网络的系统被用于数据管理和传播。这个综合数据库将为区域性肌肉骨骼组成的比较研究提供基础，并提高四肢计算模型的视觉和触觉真实感。
