Department of Radiology, Seoul National College of Medicine, Seoul National University Hospital, Seoul, South Korea.
Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, South Korea.
Thorac Cancer. 2018 Nov;9(11):1525-1527. doi: 10.1111/1759-7714.12879. Epub 2018 Sep 25.
Herein, we report the unique case of a 75-year-old male patient who had undergone a left upper lobectomy for lung cancer and developed an incidental superficial endobronchial squamous cell carcinoma in the right upper lobe that was not localizable on modern cross-sectional imaging modalities. The superficial endobronchial squamous cell carcinoma was successfully localized by computed tomography-driven virtual reality endoscopy and was identically matched with a small, whitish, patch lesion on bronchoscopy. The localized lesion was annotated on the corresponding computed tomography images, and illustrated in a fabricated three-dimensional (3D)-printed airway model. Because the exact anatomic location of the lesion and the acute angle of the adjacent bronchial trajectory were visible in the 3D model, enhanced multidisciplinary consultation resulted in the decision to treat the lesion using photodynamic therapy. Photodynamic therapy was successfully performed without complications. A follow-up bronchoscopy two months after treatment confirmed that the superficial endobronchial squamous cell carcinoma had been cured.
在此，我们报告了一例独特的病例，一名 75 岁男性患者因肺癌接受了左上肺叶切除术，随后在右上肺发现一处无法在现代横断面成像方式定位的偶发性表浅支气管内鳞状细胞癌。计算机断层扫描驱动的虚拟现实支气管镜检查成功定位了表浅支气管内鳞状细胞癌，与支气管镜下的一个小的、发白的斑块病变完全吻合。在相应的 CT 图像上标记定位病变，并在制作的三维（3D）打印气道模型中进行说明。由于在 3D 模型中可以看到病变的确切解剖位置和相邻支气管轨迹的锐角，因此增强多学科咨询后决定使用光动力疗法治疗该病变。光动力疗法成功实施，无并发症。治疗两个月后进行的随访支气管镜检查证实表浅支气管内鳞状细胞癌已治愈。
