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近距离放射疗法在肺癌治疗中——一种有价值的解决方案。

Brachytherapy in the treatment of lung cancer - a valuable solution.

作者信息

Skowronek Janusz

机构信息

Brachytherapy Department, Greater Poland Cancer Center ; Electroradiology Department, Poznan University of Medical Sciences, Poznan, Poland.

出版信息

J Contemp Brachytherapy. 2015 Aug;7(4):297-311. doi: 10.5114/jcb.2015.54038. Epub 2015 Sep 14.

Abstract

The majority of patients with lung cancer are diagnosed with clinically advanced disease. Many of these patients have a short life expectancy and are treated with palliative aim. Because of uncontrolled local or recurrent disease, patients may have significant symptoms such as: cough, dyspnea, hemoptysis, obstructive pneumonia, or atelectasis. Brachytherapy is one of the most efficient methods in overcoming difficulties in breathing that is caused by endobronchial obstruction in palliative treatment of bronchus cancer. Efforts to relieve this obstructive process are worthwhile, because patients may experience improved quality of their life (QoL). Brachytherapy plays a limited but specific role in definitive treatment with curative intent in selected cases of early endobronchial disease as well as in the postoperative treatment of small residual peribronchial disease. Depending on the location of the lesion, in some cases brachytherapy is a treatment of choice. This option is fast, inexpensive, and easy to perform on an outpatient basis. Clinical indications, different techniques, results, and complications are presented in this work.

摘要

大多数肺癌患者被诊断为临床晚期疾病。这些患者中的许多人预期寿命较短,接受姑息性治疗。由于局部疾病未得到控制或复发,患者可能会出现显著症状,如咳嗽、呼吸困难、咯血、阻塞性肺炎或肺不张。近距离放射治疗是克服支气管癌姑息治疗中由支气管内阻塞引起的呼吸困难困难的最有效方法之一。缓解这种阻塞过程的努力是值得的,因为患者的生活质量(QoL)可能会得到改善。近距离放射治疗在早期支气管内疾病的某些选定病例的根治性确定性治疗以及小的残留支气管周围疾病的术后治疗中发挥着有限但特定的作用。根据病变的位置,在某些情况下近距离放射治疗是首选治疗方法。该选择快速、廉价且易于在门诊进行。本文介绍了临床适应症、不同技术、结果和并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abfb/4643732/bc6cdf6192d7/JCB-7-25723-g001.jpg

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