Rose Jacqueline K
Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA 98225.
J Undergrad Neurosci Educ. 2018 Sep 15;16(3):A223-A231. eCollection 2018 Summer.
Due to its well-described neural circuitry and identified connectome, the model is well-suited for demonstrating connections between neuron signaling and behavioral outcome. In the 2017 FUN workshop at Dominican University, three behavior-based techniques were introduced for their ease of introduction to students, the flexible data collection options they offer and the inexpensive cost to implement in an education setting. These behavioral assays were adapted to address some of the challenges of performing behavior experiments in lab classes and included: an associative chemosensory avoidance task to examine behavior of groups of worms, a mechanosensory task to observe individual worm behavior and an optogenetics assay to directly manipulate neuron signaling and simultaneously observe resultant behavior. Methods for these assays as well as example data collected by undergraduate students in a lab class are provided. FUN Workshop feedback and assessment indicate these assays were well-received and overall seen as valuable for introducing neuroscience and behavior to undergraduates in a lab class.
由于其神经回路描述详尽且连接组已确定，该模型非常适合展示神经元信号与行为结果之间的联系。在2017年多米尼加大学举办的FUN研讨会上，介绍了三种基于行为的技术，因其易于向学生介绍、提供灵活的数据收集选项以及在教育环境中实施成本低廉。这些行为分析方法经过调整，以应对在实验课上进行行为实验所面临的一些挑战，包括：一项用于检查蠕虫群体行为的联想化学感应回避任务、一项用于观察单个蠕虫行为的机械感应任务以及一项用于直接操纵神经元信号并同时观察由此产生行为的光遗传学分析。文中提供了这些分析方法以及本科生在实验课上收集的示例数据。FUN研讨会的反馈和评估表明，这些分析方法受到了好评，总体上被认为对于在实验课上向本科生介绍神经科学和行为学非常有价值。
