Kim Hye Jeong, Choi In Ho, Jin So-Young, Park Hyeong Kyu, Byun Dong Won, Suh Kyoil, Yoo Myung Hi
Division of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
Department of Pathology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.
Int J Endocrinol. 2018 Sep 4;2018:9382649. doi: 10.1155/2018/9382649. eCollection 2018.
To evaluate shear-wave elastography (SWE) as a tool to detect postoperative cervical lymph node (LN) metastasis in patients with papillary thyroid carcinoma (PTC).
Forty-three LNs of 43 patients with PTC undergoing ultrasound (US) and SWE before ultrasound-guided fine-needle aspiration (FNA) for the evaluation of postoperative cervical LN recurrences were analyzed. The mean (), minimum (), maximum (), and standard deviation () of SWE elasticity indices were measured.
Among 43 indeterminate or suspicious LNs, 12 were malignant and 31 were benign. The , , , and values were significantly higher in malignant LNs than in benign LNs (: 37.1 kPa in malignant versus 11.8 kPa in benign LNs, < 0.001; : 11.3 kPa versus 5.1 kPa, = 0.046; : 50.5 kPa versus 23.7 kPa, < 0.001; and : 7.8 kPa versus 4.1 kPa, = 0.006). had the highest accuracy (93.0%) when applied with a cut-off value of 37.5 kPa. It had a positive likelihood ratio of 25.83 and a diagnostic odds ratio of 150.0.
The shear elasticity index of , with higher likelihood ratios for malignant LNs, may help identify postoperative cervical LN metastasis in PTC patients with indeterminate or suspicious LNs.
评估剪切波弹性成像（SWE）作为检测甲状腺乳头状癌（PTC）患者术后颈部淋巴结（LN）转移的工具。
分析43例接受超声（US）和SWE检查的PTC患者的43个淋巴结，这些患者在超声引导下细针穿刺（FNA）前接受检查以评估术后颈部LN复发情况。测量SWE弹性指数的平均值（）、最小值（）、最大值（）和标准差（）。
在43个不确定或可疑的LN中，12个为恶性，31个为良性。恶性LN的、、和值显著高于良性LN（：恶性LN为37.1kPa，良性LN为11.8kPa，<0.001；：11.3kPa对5.1kPa，=0.046；：50.5kPa对23.7kPa，<0.001；：7.8kPa对4.1kPa，=0.006）。当截断值为37.5kPa时，的准确率最高（93.0%）。其阳性似然比为25.83，诊断比值比为150.0。
的剪切弹性指数对恶性LN具有较高的似然比，可能有助于识别PTC患者中不确定或可疑LN的术后颈部LN转移。
