Complete androgen insensitivity syndrome and anti-Müllerian hormone levels before and after laparoscopic gonadectomy.

作者信息

Kusumi Maki, Mitsunami Makiko, Onoue Hiroki, Noma Momo, Matsumura Fumiko, Tabata Chisa, Tanaka Seiji, Watanabe Noriko, Kurosawa Takako, Fujiwara Toshihiro, Tsutusmi Osamu

机构信息

Center of Reproduction and Gynecologic Endoscopic Surgery, Sanno Hospital, Tokyo, Japan.

出版信息

Gynecol Minim Invasive Ther. 2017 Jul-Sep;6(3):126-128. doi: 10.1016/j.gmit.2016.11.001. Epub 2016 Dec 10.

DOI:10.1016/j.gmit.2016.11.001

PMID:30254896

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6135182/

Abstract

We report cases of two sisters with complete androgen insensitivity syndrome (CAIS). A complete female appearance, blind-ending vagina, and testes in the pelvis are characteristics of CAIS. Prophylactic laparoscopic gonadectomy was performed in both cases. Anti-Müllerian hormone (AMH) level is known to be very high in patients with CAIS; AMH is secreted by Sertoli cells and testosterone suppresses the secretion. In our cases, serum AMH was very high before gonadectomy and dramatically decreased after gonadectomy. AMH could be the diagnostic feature for patients with CAIS.

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2339/6135182/5ec6c4726ec4/GMIT-6-126-g001.jpg

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