• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

利用阴唇和前庭皮瓣自发再生能力对苗勒管发育不全患者进行单纯性阴道成形术。

Simple neovaginoplasty using spontaneous regeneration ability of labial and vestibular flap in patients with Müllerian agenesis.

作者信息

Moon Hwa Sook, Koo Jaseong, Lee Hyeyoung, Joo Bo Sun

机构信息

Center for Minimally Invasive Surgery and Treatment, Department of Obstetrics and Gynecology, Good Moonhwa Hospital, Busan, Republic of Korea.

Department of Urology, Good Moonhwa Hospital, Busan, Republic of Korea.

出版信息

Gynecol Minim Invasive Ther. 2017 Oct-Dec;6(4):173-177. doi: 10.1016/j.gmit.2017.06.004. Epub 2017 Jul 1.

DOI:10.1016/j.gmit.2017.06.004
PMID:30254908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6135190/
Abstract

OBJECTIVES

This study is aimed to introduce a simple neovaginoplasty procedure without significant complications using the spontaneous regenerative ability of labial and vestibular advancement flaps in patients with Müllerian agenesis.

MATERIALS AND METHODS

Prospectively collected data of 5 patients with vaginal agenesis due to Müllerian duct abnormality who underwent neovaginoplasty using labial and vestibular advancement flaps were retrospectively reviewed. Operative details, perioperative outcome, complications, length and width of the neovagina, and the postoperative sexual activity were evaluated.

RESULTS

The mean operation time was 48 min (range 30-60 min) and the duration of follow-up ranged from 7 to 50 months. The mean length of the neovagina was 9.6 cm × 3.5 cm and 10.8 cm × 3.5 cm at hospital discharge and at final follow-up, respectively. No significant complications occurred during or after surgery. Epithelialization was completed by 8-20 months and the time to first sexual intercourse ranged from 3 weeks to 27 months and none of the patients experienced any intercourse-related difficulties.

CONCLUSION

Our neovaginoplasty technique using labial and vestibular advancement flap is simple, safe, minimally invasive and effective while avoiding the morbidity associated with other grafting techniques.

摘要

目的

本研究旨在介绍一种简单的新阴道成形术,利用苗勒氏管发育不全患者阴唇和前庭推进皮瓣的自发再生能力,且无明显并发症。

材料与方法

回顾性分析前瞻性收集的5例因苗勒氏管异常导致阴道发育不全并接受阴唇和前庭推进皮瓣新阴道成形术患者的数据。评估手术细节、围手术期结果、并发症、新阴道的长度和宽度以及术后性行为。

结果

平均手术时间为48分钟(范围30 - 60分钟),随访时间为7至50个月。出院时和最终随访时新阴道的平均长度分别为9.6 cm×3.5 cm和10.8 cm×3.5 cm。手术期间或术后未发生明显并发症。上皮化在8 - 20个月内完成,首次性行为时间为3周 - 27个月,所有患者均未出现任何与性交相关的困难。

结论

我们使用阴唇和前庭推进皮瓣的新阴道成形术技术简单、安全、微创且有效,同时避免了与其他移植技术相关的发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c3d/6135190/83d1dd516255/GMIT-6-173-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c3d/6135190/83d1dd516255/GMIT-6-173-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c3d/6135190/83d1dd516255/GMIT-6-173-g001.jpg

相似文献

1
Simple neovaginoplasty using spontaneous regeneration ability of labial and vestibular flap in patients with Müllerian agenesis.利用阴唇和前庭皮瓣自发再生能力对苗勒管发育不全患者进行单纯性阴道成形术。
Gynecol Minim Invasive Ther. 2017 Oct-Dec;6(4):173-177. doi: 10.1016/j.gmit.2017.06.004. Epub 2017 Jul 1.
2
Novel Neovaginoplasty Using Rudimentary Uterine Horn Serosa and Pelvic Peritoneum as a Graft in Müllerian Anomalies with Vaginal Agenesis.利用残角子宫浆膜和盆腔腹膜作为移植物行阴道成形术治疗先天性无阴道合并苗勒管发育不全
J Minim Invasive Gynecol. 2019 May-Jun;26(4):657-666. doi: 10.1016/j.jmig.2018.07.004. Epub 2018 Dec 20.
3
Using the Wharton-Sheares-George method to create a neovagina in patients with Mayer-Rokitansky-Küster-Hauser syndrome: a step-by-step video tutorial.采用 Wharton-Sheares-George 法为 Mayer-Rokitansky-Küster-Hauser 综合征患者创建新阴道:分步视频教程。
Fertil Steril. 2016 Dec;106(7):e20-e21. doi: 10.1016/j.fertnstert.2016.08.030. Epub 2016 Sep 24.
4
Novel Minimally Invasive Technique of Neovaginoplasty Using an Absorbable Adhesion Barrier.使用可吸收黏附屏障的新型微创阴道再造术
J Minim Invasive Gynecol. 2020 Jan;27(1):206-211. doi: 10.1016/j.jmig.2019.02.025. Epub 2019 Jun 19.
5
Laparoscopically assisted neovaginoplasty in vaginal agenesis: a long-term outcome study in 240 patients.腹腔镜辅助阴道成形术治疗先天性无阴道:240例患者的长期疗效研究
J Pediatr Adolesc Gynecol. 2014 Dec;27(6):379-85. doi: 10.1016/j.jpag.2014.02.002. Epub 2014 Sep 23.
6
Modified Vecchietti vaginoplasty using self-made single-port laparoscopy in Mayer-Rokitansky-Küster-Hauser syndrome.改良 Vecchietti 阴道成形术结合自制单孔腹腔镜在 Mayer-Rokitansky-Küster-Hauser 综合征中的应用。
Fertil Steril. 2021 Jul;116(1):266-268. doi: 10.1016/j.fertnstert.2020.10.001. Epub 2021 Jan 15.
7
Autologous in vitro cultured vaginal tissue for vaginoplasty in women with Mayer-Rokitansky-Küster-Hauser syndrome: anatomic and functional results.自体体外培养阴道组织用于迈耶-罗基坦斯基-库斯特-豪泽综合征女性的阴道成形术:解剖学和功能结果
J Minim Invasive Gynecol. 2015 Feb;22(2):205-11. doi: 10.1016/j.jmig.2014.09.012. Epub 2014 Oct 2.
8
Evaluation of amnion in creation of neovagina in women with Mayer-Rokitansky-Kuster-Hauser syndrome.评价在 Mayer-Rokitansky-Kuster-Hauser 综合征女性中利用羊膜创建新阴道的效果。
Fertil Steril. 2017 Aug;108(2):341-345. doi: 10.1016/j.fertnstert.2017.05.026. Epub 2017 Jun 16.
9
Tilapia fish skin as a new biologic graft for neovaginoplasty in Mayer-Rokitansky-Kuster-Hauser syndrome: a video case report.罗-基-赫三联征患者阴道成形术中应用罗非鱼皮作为新型生物移植物:病例报告视频。
Fertil Steril. 2019 Jul;112(1):174-176. doi: 10.1016/j.fertnstert.2019.04.003. Epub 2019 May 15.
10
Comparing Anatomical and Functional Outcomes of Two Neovaginoplasty Techniques for Mayer-Rokitansky-Küster-Hauser Syndrome: A Ten-Year Retrospective Study with Swine Small Intestinal Submucosa and Homologous Skin Grafts.比较两种用于 Mayer-Rokitansky-Küster-Hauser 综合征的新阴道成形术技术的解剖学和功能结果:一项使用猪小肠黏膜下层和同种异体皮肤移植的十年回顾性研究。
Ther Clin Risk Manag. 2023 Jul 4;19:557-565. doi: 10.2147/TCRM.S415672. eCollection 2023.

引用本文的文献

1
Clinical pilot study to evaluate the neovaginal PACIENA prosthesis® for vaginoplasty without skin grafts in women with vaginal agenesis.临床初步研究评估用于阴道成形术的 PACIENA 阴道假体(®),该手术无需进行皮片移植,适用于阴道发育不全的女性。
BMC Womens Health. 2019 Nov 26;19(1):144. doi: 10.1186/s12905-019-0841-z.
2
A case of Mayer-Rokitansky-Küster-Hauser syndrome in a low-resource tertiary hospital in Douala, Cameroon.喀麦隆杜阿拉一家资源匮乏的三级医院里的一例迈耶-罗基坦斯基-库斯特-豪泽综合征病例。
SAGE Open Med Case Rep. 2019 Feb 13;7:2050313X19830817. doi: 10.1177/2050313X19830817. eCollection 2019.

本文引用的文献

1
Laparoscopically assisted cervical canalization and neovaginoplasty in a woman with cervical atresia and vaginal aplasia.腹腔镜辅助下对一名宫颈闭锁和阴道发育不全女性进行宫颈管疏通及新阴道成形术。
Gynecol Minim Invasive Ther. 2017 Jan-Mar;6(1):31-33. doi: 10.1016/j.gmit.2016.05.001. Epub 2016 Jun 7.
2
Laparoscopic Neovagina and Neocervix Followed By Reconstruction With PTFE Graft/Buccal Mucosa and Pudendal Artery Perforator Flap.
J Minim Invasive Gynecol. 2015 Nov-Dec;22(6S):S125. doi: 10.1016/j.jmig.2015.08.377. Epub 2015 Oct 15.
3
Long-term outcomes of transvestibular vaginoplasty with pelvic peritoneum in 182 patients with Rokitansky's syndrome.182 例 ROKITANSKY 综合征患者经颅外阴道成形术联合盆腔腹膜移植的长期疗效。
Fertil Steril. 2010 Nov;94(6):2281-5. doi: 10.1016/j.fertnstert.2010.02.010. Epub 2010 Mar 19.
4
Sexuality after laparoscopic peritoneal vaginoplasty in women with Mayer-Rokitansky-Kuster-Hauser syndrome.腹腔镜腹膜阴道成形术后 Mayer-Rokitansky-Kuster-Hauser 综合征女性的性生活。
J Minim Invasive Gynecol. 2009 Nov-Dec;16(6):720-9. doi: 10.1016/j.jmig.2009.07.018.
5
Creation of a neovagina by Davydov's laparoscopic modified technique in patients with Rokitansky syndrome.利用 Davydov 腹腔镜改良技术为 Rokitansky 综合征患者创建新阴道。
Am J Obstet Gynecol. 2010 Jan;202(1):33.e1-6. doi: 10.1016/j.ajog.2009.08.035. Epub 2009 Nov 4.
6
Current evaluation of amenorrhea.闭经的当前评估
Fertil Steril. 2008 Nov;90(5 Suppl):S219-25. doi: 10.1016/j.fertnstert.2008.08.038.
7
XIV. The Formation of an Artificial Vagina by Intestinal Trransplantation.十四、通过肠道移植形成人工阴道
Ann Surg. 1904 Sep;40(3):398-403.
8
Normalization of the vagina by dilator treatment alone in Complete Androgen Insensitivity Syndrome and Mayer-Rokitansky-Kuster-Hauser Syndrome.仅通过扩张器治疗使完全性雄激素不敏感综合征和 Mayer-Rokitansky-Kuster-Hauser 综合征患者的阴道正常化。
Hum Reprod. 2007 Jul;22(7):2020-4. doi: 10.1093/humrep/dem074. Epub 2007 Apr 20.
9
[Laparoscopic Davydov or laparoscopic transposition of the peritoneal colpopoeisis described by Davydov for the treatment of congenital vaginal agenesis: the technique and its evolution].
Gynecol Obstet Fertil. 2004 Dec;32(12):1023-30. doi: 10.1016/j.gyobfe.2004.10.012.
10
Long-term results after neovagina creation in Mayer-Rokitanski-Kuster-Hauser syndrome by Vecchietti's operation.
Eur J Obstet Gynecol Reprod Biol. 2002 Jul 10;103(2):168-72. doi: 10.1016/s0301-2115(02)00031-3.