职业性遗留问题：威斯康星州恶性间皮瘤的发病率和死亡率。
An Occupational Legacy: Malignant Mesothelioma Incidence and Mortality in Wisconsin.
机构信息
Wisconsin Department of Health Services, Division of Public Health, Bureau of Environmental and Occupational Health, Madison, WI (Dr Tomasallo, Dr Christensen, Ms Raymond, Dr Creswell, Dr Anderson, and Dr Meiman); Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI (Dr Christensen); Department of Population Health Sciences, University of Wisconsin-Madison, Madison, WI (Ms Raymond, Dr Creswell, and Dr Anderson).
出版信息
J Occup Environ Med. 2018 Dec;60(12):1143-1149. doi: 10.1097/JOM.0000000000001461.
OBJECTIVES
The aim of the study was to describe mesothelioma occurrence in Wisconsin from 1997 to 2013 by usual industry and occupation (I&O), including occupations generally considered low risk.
METHODS
Population-based rates and standardized incidence and mortality ratios were calculated. Two case-control analyses were designed to compare mesothelioma incidence and mortality in specific I&O groups with occurrence of (1) brain and central nervous system cancers and (2) other causes of death, using logistic regression.
RESULTS
Mesothelioma incidence and mortality were elevated in Wisconsin (SIRadj = 1.20 [1.13 to 1.28]; SMRadj = 1.30 [1.22 to 1.38]). Certain industry (construction, manufacturing) and occupation (construction and extraction) groups were associated with increased odds of mesothelioma, with some evidence of increased risk among teachers.
CONCLUSIONS
Forty years after the Occupational and Safety Health Act, mesothelioma incidence and mortality remain elevated in Wisconsin, with increased risk continuing for certain I&O groups.
目的
本研究旨在描述 1997 年至 2013 年期间威斯康星州间皮瘤的发病情况，涉及通常被认为低风险的职业。
方法
计算基于人群的发病率、标准化发病比和死亡比。设计了两项病例对照分析，使用逻辑回归比较特定行业和职业组间的间皮瘤发病率和死亡率与（1）脑和中枢神经系统癌症以及（2）其他死亡原因的发生情况。
结果
威斯康星州间皮瘤的发病率和死亡率升高（调整后的发病率比 [SIRadj] = 1.20 [1.13 至 1.28]；调整后的死亡率比 [SMRadj] = 1.30 [1.22 至 1.38]）。某些行业（建筑、制造业）和职业（建筑和采掘）与间皮瘤的发病风险增加相关，教师的风险增加证据也有所增加。
结论
职业安全与健康法案颁布 40 年后，威斯康星州间皮瘤的发病率和死亡率仍然升高，某些行业和职业组的风险持续增加。
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