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中草药制剂在儿童中的潜在不良后果。

Potential adverse outcomes of herbal preparation use in childhood.

机构信息

School of Medicine, The University of Adelaide, Adelaide, SA, Australia.

出版信息

Acta Paediatr. 2019 Mar;108(3):419-422. doi: 10.1111/apa.14595. Epub 2018 Oct 17.

Abstract

AIM

Complementary and alternative medicines are becoming increasingly popular worldwide with a variety of purported medicinal uses. These products are generally believed to be natural and therefore safe, with few adverse reactions. With this perception, parents are now taking their children to see practitioners prescribing these medicines as well as self-prescribing. Despite this, there are issues regarding safety, efficacy and regulation, with increasing numbers of reports of adverse reactions to these products. Therefore, a mini-review was conducted to ascertain the potential risks to children.

METHODS

A overview of literature was conducted to highlight the current use of complementary and alternative medicines in children and the possible risks associated with their use.

RESULTS

Infants and children may be more susceptible to harmful effects due to their immature physiology and metabolic pathways and different dosage requirements. Adverse reactions may also be caused by interactions with conventional medicines, contamination with heavy metals, and adulteration of filler products including other plant species or pharmaceutical agents.

CONCLUSION

As complementary and alternative medicines become increasingly used alongside and with conventional drug therapy, there needs to be greater awareness and discussion among parents, complementary practitioners and medical practitioners to ensure the overall health and safety of children being exposed to these products.

摘要

目的

随着各种所谓的药用用途,补充和替代医学在世界范围内越来越受欢迎。这些产品通常被认为是天然的,因此安全性高,不良反应较少。由于这种观念,现在父母会带孩子去看开这些药物的从业者,也会自行开这些药物。尽管如此,这些产品的安全性、疗效和监管仍存在问题,越来越多的报告称这些产品有不良反应。因此,进行了一个小型综述以确定这些产品对儿童的潜在风险。

方法

对文献进行综述,以强调补充和替代医学在儿童中的当前用途,以及与其使用相关的可能风险。

结果

由于婴儿和儿童的生理和代谢途径不成熟,以及不同的剂量要求,他们可能更容易受到有害影响。不良反应也可能是由于与常规药物相互作用、重金属污染以及填充剂产品(包括其他植物物种或药物制剂)掺假引起的。

结论

随着补充和替代医学与常规药物治疗一起越来越多地被使用,父母、补充治疗师和医疗从业者之间需要有更多的意识和讨论,以确保接触这些产品的儿童的整体健康和安全。

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