State Key Laboratory of Digital Manufacturing Equipment and Technology, School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
PLoS One. 2018 Sep 26;13(9):e0204492. doi: 10.1371/journal.pone.0204492. eCollection 2018.
Accurate estimation of motion field in respiration-correlated 4DCT images, is a precondition for the analysis of patient-specific breathing dynamics and subsequent image-supported treatment planning. However, the lung motion estimation often suffers from the sliding motion. In this paper, a novel lung motion method based on the non-rigid registration of point clouds is proposed, and the tangent-plane distance is used to represent the distance term, which describes the difference between two point clouds. Local affine transformation model is used to express the non-rigid deformation of the lung motion. The final objective function is expressed in the Frobenius norm formation, and matrix optimization scheme is carried out to find out the optimal transformation parameters that minimize the objective function. A key advantage of our proposed method is that it alleviates the requirement that the source point cloud and the reference point cloud should be in one-to-one corresponding relationship, and the requirement is difficult to be satisfied in practical application. Furthermore, the proposed method takes the sliding motion of the lung into consideration and improves the registration accuracy by reducing the constraint of the motion along the tangent direction. Non-rigid registration experiments are carried out to validate the performance of the proposed method using popi-model data. The results demonstrate that the proposed method outperforms the traditional method with about 20% accuracy increase.
准确估计呼吸相关 4DCT 图像中的运动场,是分析患者特定呼吸动力学和随后的图像支持治疗计划的前提。然而,肺部运动估计常常受到滑动运动的影响。本文提出了一种基于点云非刚性配准的新型肺部运动方法,并用切平面距离表示距离项,该距离项描述了两个点云之间的差异。采用局部仿射变换模型来表示肺部运动的非刚性变形。最终的目标函数表示为 Frobenius 范数的形式,并采用矩阵优化方案找到最小化目标函数的最优变换参数。我们提出的方法的一个主要优点是,它减轻了对点云源和参考点云应具有一一对应关系的要求,而在实际应用中,这种要求很难得到满足。此外,该方法考虑到了肺部的滑动运动,并通过减少沿切向方向运动的约束来提高配准精度。利用 popi-model 数据进行非刚性配准实验,验证了所提出方法的性能。结果表明,与传统方法相比,所提出的方法的准确性提高了约 20%。