Boysen Philip G, Pappas Marisa M, Evans Bryan
Department of Anesthesiology, Ochsner Clinic Foundation, New Orleans, LA.
The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA.
Ochsner J. 2018 Summer;18(2):121-125. doi: 10.31486/toj.17.0072.
The epidemic of opioid abuse is increasing, and the number of deaths secondary to opioid overdose is also increasing. Recent attention has focused on opioid prescribing and management of chronic pain. However, opioid use in perioperative and periprocedural patients, whether they have chronic pain or exhibit new persistent opioid abuse after a procedure, has received little attention.
We present an evidence-based technique that combines subanesthetic infusions of lidocaine and dexmedetomidine supplemented with other intravenous agents and a low dose of inhaled anesthetic.
Based on evidence of drug action and interaction, an opioid-free anesthetic can be delivered successfully. We present the cases of 2 patients in whom the opioid-free anesthetic technique was used with a successful outcome, adequate pain management, and avoidance of opioid drugs.
This anesthetic prescription can be useful for opioid-naïve patients as well as for patients with chronic pain that is managed with opioids.
阿片类药物滥用的流行情况正在增加,因阿片类药物过量导致的死亡人数也在上升。最近的关注焦点集中在阿片类药物的处方开具及慢性疼痛的管理上。然而,围手术期和围操作期患者使用阿片类药物的情况,无论他们是否患有慢性疼痛或在手术后出现新的持续性阿片类药物滥用,都很少受到关注。
我们提出一种基于证据的技术,该技术将利多卡因和右美托咪定的亚麻醉剂量输注与其他静脉药物及低剂量吸入麻醉剂相结合。
基于药物作用和相互作用的证据,可以成功实施无阿片类药物麻醉。我们展示了2例使用无阿片类药物麻醉技术并取得成功结果、充分疼痛管理且避免使用阿片类药物的病例。
这种麻醉处方对未使用过阿片类药物的患者以及使用阿片类药物管理慢性疼痛的患者可能有用。