Jordan Lewis A, Green Lauren
University of Illinois College of Medicine, 1835 W Polk St, Chicago IL 60612 USA.
Radiol Case Rep. 2018 Sep 20;13(6):1238-1241. doi: 10.1016/j.radcr.2018.08.029. eCollection 2018 Dec.
Since breast cancer is the most common non-skin cancer in women and the second most common cause of cancer death in women, it is important to understand potential sites of metastasis, including rare sites that have not frequently been reported in the literature. As our cancer interventions improve, patients will live longer and we will potentially see unusual patterns of metastatic disease more frequently, as in our case of a woman with breast cancer metastasis to her urinary bladder.
We report a case of a 77-year-old female with history of breast cancer, metastatic to bone, and recently diagnosed bilateral hydronephrosis, secondary to a new urinary bladder mass. This mass presented 30 years after her initial cancer diagnosis and biopsy confirmed that the origin was most likely metastatic pleomorphic lobular carcinoma of breast origin.
This case raises the possibility that unusual patterns of cancer metastasis may become more common, as life expectancy of cancer patients increases. This creates unique diagnostic and management challenges for radiologists and all members of the health care team.
由于乳腺癌是女性中最常见的非皮肤癌,也是女性癌症死亡的第二大常见原因,了解潜在的转移部位非常重要,包括文献中不常报道的罕见部位。随着我们癌症干预措施的改进,患者寿命将延长,我们可能会更频繁地看到不寻常的转移疾病模式,就像我们遇到的一名乳腺癌转移至膀胱的女性患者。
我们报告一例77岁女性,有乳腺癌病史,已转移至骨,最近诊断为双侧肾积水,继发于新出现的膀胱肿块。该肿块在她最初癌症诊断30年后出现,活检证实其起源最可能是乳腺来源的转移性多形性小叶癌。
随着癌症患者预期寿命的增加,这种不寻常的癌症转移模式可能会变得更加常见。这给放射科医生和医疗团队的所有成员带来了独特的诊断和管理挑战。