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钛涂层网片与标准聚丙烯网片在腹腔镜腹股沟疝修补术中的应用:一项前瞻性、随机、对照临床试验。

Titanium-coated mesh versus standard polypropylene mesh in laparoscopic inguinal hernia repair: a prospective, randomized, controlled clinical trial.

机构信息

Department of Hernia and Abdominal wall Surgery, Beijing Chao-Yang Hospital, No. 5 JingYuan Road, Shijingshan District, Beijing, 100043, China.

出版信息

Hernia. 2019 Apr;23(2):255-259. doi: 10.1007/s10029-018-1823-z. Epub 2018 Sep 27.

DOI:10.1007/s10029-018-1823-z
PMID:30259252
Abstract

OBJECTIVE

We aimed to compare the clinical outcome of titanium-coated mesh and polypropylene mesh in laparoscopic inguinal hernia repair.

METHODS

A total of 102 patients who received laparoscopic inguinal hernia repair in January-June 2016 in Beijing Chao-Yang Hospital were enrolled in this study. Patients were randomly divided into two groups, receiving either titanium-coated mesh (n = 50) or standard polypropylene mesh (n = 52). Multiple clinical parameters were collected and analyzed, including clinical manifestations, operative time, intraoperative blood loss, hospital stay, hospital cost, recovery time, and postoperative complications.

RESULTS

All procedures were completed. A statistical difference between two groups was not identified in regards to operative time, intraoperative blood loss, hospital stay, and recovery time (P > 0.05). Three cases with seroma and 15 with foreign body sensation were reported in the titanium-coated mesh group; 9 cases with seroma and 17 with foreign body sensation were reported in the standard polypropylene mesh group. There was no significant difference in the incidence of seroma and/or foreign body sensation. A lower hospital cost but longer recovery period was documented in the standard polypropylene mesh group (P < 0.05). No recurrence, infection or chronic pain was observed during 1-year follow-up in both groups.

CONCLUSION

Titanium-coated mesh possesses comparable clinical qualities as the standard polypropylene mesh but with a shorter recovery period. Therefore, this mesh is promising for clinical practice though the cost is higher than the standard polypropylene mesh.

摘要

目的

比较钛涂层网片与聚丙烯网片在腹腔镜腹股沟疝修补术中的临床疗效。

方法

2016 年 1 月至 6 月在北京朝阳医院接受腹腔镜腹股沟疝修补术的 102 例患者纳入本研究。患者随机分为两组,分别接受钛涂层网片(n=50)或标准聚丙烯网片(n=52)治疗。收集并分析了多种临床参数,包括临床表现、手术时间、术中出血量、住院时间、住院费用、恢复时间和术后并发症。

结果

所有手术均顺利完成。两组在手术时间、术中出血量、住院时间和恢复时间方面无统计学差异(P>0.05)。钛涂层网片组有 3 例出现血清肿,15 例出现异物感;标准聚丙烯网片组有 9 例出现血清肿,17 例出现异物感。两组血清肿和/或异物感的发生率无统计学差异。标准聚丙烯网片组的住院费用较低,但恢复时间较长(P<0.05)。两组在 1 年随访期间均未观察到复发、感染或慢性疼痛。

结论

钛涂层网片与标准聚丙烯网片具有相当的临床质量,但恢复时间更短。因此,尽管成本高于标准聚丙烯网片,但这种网片具有良好的应用前景。

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