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在海地太子港的一个艾滋病诊所整合高血压服务:来自现场的报告。

Integrating hypertension services at an HIV clinic in Port-au-Prince, Haiti: A report from the field.

机构信息

Center for Global Health, Department of Medicine, Weill Cornell Medicine, New York City, New York.

The Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.

出版信息

J Clin Hypertens (Greenwich). 2018 Oct;20(10):1485-1492. doi: 10.1111/jch.13392. Epub 2018 Sep 26.

Abstract

HIV-positive adults with hypertension have increased risk of mortality but HIV clinics often do not provide hypertension care. The authors integrated hypertension management into existing HIV services at a large clinic in Haiti. Of 1729 documented HIV-positive adults presenting for care at the GHESKIO HIV clinic between March and July 2016, 551 screened positive for hypertension, with systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg. A convenience sample of 100 patients from this group received integrated hypertension and HIV care for 6 months. At time of identification, patients were screened for proteinuria and initiated on antihypertensive medication. Hypertension and HIV visits coincided; medications were free. Outcomes were retention in care and change in blood pressure over 6 months. Average blood pressure over 6 months was described using linear mixed-effects model. Of 100 HIV-positive adults with hypertension referred for integrated care, three were ineligible due to comorbidities. Among 97 participants, 82% (N = 80) remained in care at 6 months from time of positive hypertension identification. 96% (N = 93) were on antiretroviral therapy with median CD4+ count of 442 cells/µL (IQR 257-640). Estimated average blood pressure over 6 months decreased from systolic 160 mmHg (CI 156, 165) to 146 mmHg (CI 141, 150), P-value <0.0001, and diastolic 105 mmHg (CI 102, 108) to 93 mmHg (CI 89, 96), P-value <0.0001. HIV and hypertension management were successfully integrated at a HIV clinic in Haiti. Integrated management is essential to combat the growing burden of cardiovascular disease among HIV-positive adults.

摘要

HIV 阳性合并高血压的成年人死亡率增加,但 HIV 诊所通常不提供高血压护理。作者在海地的一家大型诊所将高血压管理整合到现有的 HIV 服务中。在 2016 年 3 月至 7 月期间,1729 名有记录的 HIV 阳性成年人在 GHESKIO HIV 诊所就诊,其中 551 名筛查出高血压,收缩压≥140mmHg 和/或舒张压≥90mmHg。从该组中随机抽取 100 名患者接受 6 个月的综合高血压和 HIV 护理。在识别时,对患者进行蛋白尿筛查并开始使用降压药物。高血压和 HIV 就诊同时进行,药物免费。结果是 6 个月时的护理保留率和血压变化。使用线性混合效应模型描述 6 个月的平均血压。在被转诊接受综合护理的 100 名 HIV 阳性合并高血压患者中,有 3 名因合并症而不合格。在 97 名参与者中,有 82%(N=80)在从高血压阳性识别开始的 6 个月时保持护理。96%(N=93)正在接受抗逆转录病毒治疗,中位数 CD4+计数为 442 个/µL(IQR 257-640)。估计的平均血压在 6 个月内从收缩压 160mmHg(CI 156,165)下降到 146mmHg(CI 141,150),P 值<0.0001,舒张压从 105mmHg(CI 102,108)下降到 93mmHg(CI 89,96),P 值<0.0001。在海地的一家 HIV 诊所成功地整合了 HIV 和高血压管理。综合管理对于应对 HIV 阳性成年人中日益增加的心血管疾病负担至关重要。

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