Lind Ole Christian, Helen Oughton Deborah, Salbu Brit
a CERAD CoE, Faculty of Environmental Sciences and Natural Resource Management , Norwegian University of Life Sciences , Aas , Norway.
Int J Radiat Biol. 2019 Jan;95(1):76-81. doi: 10.1080/09553002.2018.1516906. Epub 2018 Sep 28.
Derivation of dose-response relationships for exposed organisms and their sensitive life history stages requires in-house experiments under well-defined, controlled conditions. In the present work we describe the FIGARO low dose gamma irradiation facility at the Norwegian University of Life Sciences, Ås, Norway, which is managed by the Centre of Environmental Radioactivity (CERAD CoE).
The CERAD/NMBU facility opened in 2003, and was upgraded to a climate controlled facility in 2012, supported by the EU DoReMi project. The Co irradiation source provides a continuous dose rate field from 3 Gy/hr down to 0.4 mGy/hr when maximally loaded (400 GBq). The FIGARO low dose gamma irradiation facility allows simultaneous acute to chronic exposure of organisms over the whole dose-rate field. The facility is licensed for a number of different test organisms, including GMOs, and can be used in combination with other stressors such as trace metals and UV radiation.
推导受暴露生物及其敏感生活史阶段的剂量-反应关系需要在明确界定、可控的条件下进行内部实验。在本研究中，我们描述了位于挪威奥斯的挪威生命科学大学的FIGARO低剂量伽马辐照设施，该设施由环境放射性中心（CERAD卓越中心）管理。
CERAD/NMBU设施于2003年启用，并于2012年在欧盟DoReMi项目的支持下升级为气候控制设施。钴辐照源在最大负载（400GBq）时可提供从3 Gy/小时到0.4 mGy/小时的连续剂量率场。FIGARO低剂量伽马辐照设施允许在整个剂量率范围内对生物进行同时的急性到慢性暴露。该设施已获得多种不同测试生物（包括转基因生物）的许可，并且可与其他应激源（如痕量金属和紫外线辐射）结合使用。
